SynthesisEuropean child & adolescent psychiatry2025
Prevalence, severity and risk factors for mental disorders among sexual and gender minority young people: a systematic review of systematic reviews and meta-analyses.
Synthesis in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Suicide Risk Among Transgender Adolescents and Young Adults: A Meta-Analysis of Nearly One Million Participants.International journal of methods in psychiatric research · 2026Pooled it
- A socially assistive robot to support mental wellbeing in LGBTQ+ young people at risk of self-harm: a randomized controlled trial.Nature medicine · 2026Trial
- Mental health disparities in LGBTQIA+ populations: an umbrella review of systematic reviews and meta-analyses.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Gender and other diversity-related factors in psychiatric hospital care: protocol for the participatory mixed-methods PSY-DIVER study.BMC psychiatry · 2026Article
- Childhood adversity subgroups and their associations with mental health symptoms among Rhode Island young adults.Social psychiatry and psychiatric epidemiology · 2026Article
- Mental Health Service Use in Sexually and Gender Diverse Youths and Cisgender Heterosexual Youths.JAMA network open · 2026Article
- Exploring Cultural Knowledge in Clinical Work with LGBTQIA+ Patients: A Qualitative Study of Italian Mental Health Professionals.Healthcare (Basel, Switzerland) · 2026Article
- Optimizing Engagement with Digital Mental Health Resources Among Sexual and Gender Minority Users: Protocol for a Series of Microrandomized Trials.JMIR research protocols · 2026Article
- Social media use and health outcomes as moderated by rurality among sexual minority young adults.The American journal on addictions · 2026Article
- Reducing Disparities and Improving Mental Health for Transgender Persons.Alpha psychiatry · 2026Article
- Different stigmas, different patterns: unfair treatment maps onto bullying involvement through internalizing and externalizing problems.Frontiers in psychology · 2026Article
- High burden of depressive symptoms among sexual and gender diverse persons in Brazil: The role of discrimination, internalized homonegativity, and race.PLOS global public health · 2026Article
- [Sex/Gender in psychotherapy].Der Nervenarzt · 2026Review
- The moderating role of HIV status in the association between gender identity and depression among sexual and gender minorities in Abuja, Nigeria.PLOS mental health · 2026Article
- Resilience and distinct lifeways: sexual orientation and gender minority status differences in health, well-being, and social determinants of health in a population-based sample of older adults.BMC public health · 2025Article
- Gender Differences in Trajectories of Depressive Symptoms Among Talkspace Clients: Naturalistic Observational Study.JMIR formative research · 2025Observational
- Sexual minority populations and disparities in cardiovascular healthcare.European heart journal · 2025Review
- Mortality among transgender persons: a Taiwan matched-population and sibling-comparison cohort study.The Lancet regional health. Western Pacific · 2025Article
- Intersectional Disparities in Digital Health and Mental Health Service Use Among US Youth During the COVID-19 Pandemic: Cross-Sectional Analysis of a National Survey.Journal of medical Internet research · 2025Article
- Psychological distress and well-being in university and high school students: a cross-sectional study in Italy.BMJ open · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests heightened prevalence and severity of mental disorders among sexual minority (SM) and gender minority (GM) young people. Several risk factors have been associated with these disparities. A systematic review of systematic reviews and meta-analysis was conducted to provide a comprehensive overview of the literature and to determine the field's current position. MEDLINE, PsycInfo, Scopus and Web of Science were searched in March 2022 and updated January 2024. Eligibility criteria were systematic reviews or meta-analyses assessing contemporaneous prevalence, severity and/or risk factors of mental disorders among SM or GM young people aged 25 and under. 42 reviews were included, all of which were low quality. The prevalence of depression among SM was 26% (95% CI 21-32%), and among GM was 46% (95% CI 36-56%). Greater depression severity was found among SM compared to heterosexual young people, with a significant albeit small effect size (Hedges' g = 0.38, 95% CI = 0.25 to 0.50); effect sizes were similar when separating by gender. GM also reported greater symptom severity compared to cisgender young people. Other mental disorders were more prevalent compared to those reported in the general population, and of greater severity compared to heterosexual/cisgender young people. Several proximal and distal risk factors were focused upon within the systematic reviews identified. Past systematic reviews consistently indicate a heightened risk of mental disorders among SM and GM young people. Services need to be aware of these disparities and adapt their care accordingly.
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