Evidence map›Paper›PMID 39139835›Full record

ArticleJournal of oral microbiology2024

Targeted elimination of

Nil Yakar, Ozge Unlu, Lujia Cen, Hatice Hasturk, Tsute Chen, Wenyuan Shi, Xuesong He, Alpdogan Kantarci

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. IsGut microbes · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Characterisation of novelJournal of oral microbiology · 2025
    Article
  14. Impact ofFrontiers in immunology · 2025
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nil YakarImmunology and Infectious Diseases, The ADA Forsyth Institute, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-0568-0928
Ozge UnluImmunology and Infectious Diseases, The ADA Forsyth Institute, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-5411-5925
Lujia CenDepartment of Microbiology, The ADA Forsyth Institute, Cambridge, MA, USA.
Hatice HasturkImmunology and Infectious Diseases, The ADA Forsyth Institute, Cambridge, MA, USA.
Tsute ChenDepartment of Microbiology, The ADA Forsyth Institute, Cambridge, MA, USA.
Wenyuan ShiDepartment of Microbiology, The ADA Forsyth Institute, Cambridge, MA, USA.
Xuesong HeDepartment of Microbiology, The ADA Forsyth Institute, Cambridge, MA, USA.
Alpdogan KantarciImmunology and Infectious Diseases, The ADA Forsyth Institute, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-2679-9100

Funding

Mechanistic link between Alzheimer's disease and periodontitisRF1AG062496 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI DEDEOGLU, ALPASLAN, KANTARCI, IBRAHIM ALPDOGAN · 2019 to 2019
$3.7M
Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbesR01DE030943 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI Xuesong He · 2022 to 2026
$2.4M
NIA NIH HHS RF1 AG062496NIDCR NIH HHS R01 DE030943
6 · The paper itself

Abstract

Background: Methods: A multispecies bacterial community was cultured and treated with two concentrations of FP-100 over two days. Microbial profiles were examined at 24-h intervals using 16S rRNA sequencing. A ligature-induced periodontitis mouse model was employed to test FP-100 in vivo. Results: FP-100 significantly reduced Conclusion: FP-100 effectively eliminates

Indexed as

Antimicrobial agentsFusobacterium nucleatumhygromycin aperiodontal bone lossperiodontal disease

Identifiers

PMID39139835
PMCPMC11321114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.