Evidence map›Paper›PMID 39139814›Full record

ArticleJournal of biomedical optics2024

Monte Carlo simulation of the effect of melanin concentration on light-tissue interactions for transmittance pulse oximetry measurement.

Raghda Al-Halawani, Meha Qassem, Panicos A Kyriacou

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raghda Al-HalawaniCity, University of London, Research Centre for Biomedical Engineering, London, United Kingdom.ORCID 0000-0002-6193-921X
Meha QassemCity, University of London, Research Centre for Biomedical Engineering, London, United Kingdom.ORCID 0000-0003-0730-3189
Panicos A KyriacouCity, University of London, Research Centre for Biomedical Engineering, London, United Kingdom.ORCID 0000-0002-2868-485X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Questions about the accuracy of pulse oximeters in measuring arterial oxygen saturation ( Aim: We aim to use computational modeling to identify the potential causes of inaccuracy in Approach: An Results: Moderate and dark skin calibration curve equations were different from light skin, suggesting that a single algorithm may not be suitable for all skin types due to the varying behavior of light in different epidermal melanin concentrations, especially at 660 nm. The ratio between the mean bias in White and Black subjects in the cohort study was 6.6 and 5.47 for light and dark skin, respectively, from the Monte Carlo model. A linear multiplication factor of 1.23 and exponential factor of 1.8 were applied to moderate and dark skin calibration curves, resulting in similar alignment. Conclusions: This study underpins the careful re-assessment of pulse oximeter designs to minimize bias in

Indexed as

MelaninsMonte Carlo MethodOximetrySkin PigmentationAlgorithmsCalibrationComputer SimulationFingersHumansLightOxygenOxygen SaturationSkinMelaninsOxygencalibrationmelaninMonte Carlo simulationpulse oximetryskin pigmentation

Identifiers

PMID39139814
PMCPMC11321364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.