ArticleMultiple sclerosis journal - experimental, translational and clinical
Pregnancy characteristics in Egyptian female patients with NMOSD.
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Case Report: Unplanned pregnancy during treatment with inebilizumab in patients with AQP4-IgG-seropositive NMOSD: report of two cases.Frontiers in immunology · 2026Article
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Authors and funding
7 authors.
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Abstract
Background: Neuromyelitis optica spectrum disorder (NMOSD) primarily affects women of childbearing age. Objectives: Studying the potential relationship between NMOSD and pregnancy characteristics and outcomes. Subjects and methods: This is a retrospective cohort study that was conducted on 66 married female patients diagnosed with NMOSD. All patients underwent a thorough review of their demographic and clinical history through their medical records and personal interviews. Additionally, a complete neurological examination was performed, along with the expanded disability status scale (EDSS) and a pregnancy registry questionnaire. Results: After comparing married patients before and after disease onset, there was a significant increase in the number of abortions and the percentage of cesarean sections, as well as a decrease in the percentage of breastfeeding after disease onset. The Conclusion: Presence of NMOSD increased the percentage of miscarriage, delivery by cesarean section, and decreased the chance of breastfeeding. In addition, pregnancy increases NMOSD relapse and subsequent disability.
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