Evidence map›Paper›PMID 39139650›Full record

ArticleFrontiers in nutrition2024

Dietary supplementation with mulberry leaf flavonoids and carnosic acid complex enhances the growth performance and antioxidant capacity via regulating the p38 MAPK/Nrf2 pathway.

Chunming Liu, Hui Huang, Yulian Chen, Yingjun Zhou, Tiantian Meng, Bihui Tan, Wenxiang He, Xiaoqin Fu, Dingfu Xiao

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Biological functions and applications of rosemary extracts in animal production.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Effect of dietary supplementation withFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunming Liu *College of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Hui Huang *College of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Yulian ChenCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Yingjun ZhouCollege of Xiangya Pharmaceutical Sciences, Central South University, Changsha, China.
Tiantian MengCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Bihui TanCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Wenxiang HeCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Xiaoqin FuCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Dingfu XiaoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to investigate the regulatory effects of mulberry leaf flavonoids and carnosic acid complex (MCC) on the growth performance, intestinal morphology, antioxidant, and p38 MAPK/Nrf2 pathway in broilers. Methods: A total of 256 healthy 8-day-old female yellow-feathered broilers were randomly divided into 4 equal groups: a control group (CON) fed a basal diet, an antibiotic group (CTC) supplemented with 50 mg/kg chlortetracycline, and two experimental groups (MCC75, MCC150) fed basal diets with 75 mg/kg and 150 mg/kg of MCC, respectively. The experiment lasted for 56 days, with days 1-28 designated as the initial phase and days 29-56 as the growth phase. Results: The results on the growth performance showed that diets supplemented with MCC and CTC decreased the feed-to-gain ratio (F/G), diarrhea rate, and death rate, while significantly increasing the average daily weight gain (ADG) ( Discussion: These findings indicate that dietary supplementation with MCC, particularly at a dosage of 150 mg/kg, may serve as a viable antibiotic alternative, enhancing growth performance, intestinal health, and antioxidant capacity in broilers by regulating the p38-MAPK/Nrf2 pathway.

Indexed as

antioxidantbroilercarnosic acidgrowth performancemulberry leaf flavonoids

Identifiers

PMID39139650
PMCPMC11319276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.