Evidence map›Paper›PMID 39139360›Full record

ArticleArthroplasty today2024

Antiseptics' Concentration, Combination, and Exposure Time on Bacterial and Fungal Biofilm Eradication.

Emanuela Roscetto, Donato Di Gennaro, Tiziana Ascione, Umberto Galdiero, Martina Aversa, Enrico Festa, Maria Rosaria Catania, Giovanni Balato

Abstract read
In one paragraph

Article in Arthroplasty today, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emanuela RoscettoDepartment Molecular Medicine and Medical Biotechnology, "Federico II" University, Naples, Italy.
Donato Di GennaroSection of Orthopaedic Surgery, Department of Public Health, "Federico II" University, Naples, Italy.
Tiziana AscioneDepartment of Medicine, Service of Infectious Disease, Cardarelli Hospital Naples, Naples, Italy.
Umberto GaldieroDepartment Molecular Medicine and Medical Biotechnology, "Federico II" University, Naples, Italy.
Martina AversaDepartment Molecular Medicine and Medical Biotechnology, "Federico II" University, Naples, Italy.
Enrico FestaSection of Orthopaedic Surgery, Department of Public Health, "Federico II" University, Naples, Italy.
Maria Rosaria CataniaDepartment Molecular Medicine and Medical Biotechnology, "Federico II" University, Naples, Italy.
Giovanni BalatoSection of Orthopaedic Surgery, Department of Public Health, "Federico II" University, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aims to assess the activity of solutions containing povidone-iodine (PI) and hydrogen peroxide (H Methods: Different antiseptic solutions were tested on 2-day-old biofilms of Gram-positive and Gram-negative bacteria and fungi at 1 and 3 minutes of exposure. The efficacy of these solutions was evaluated by measuring the biofilm metabolic activity by methoxynitrosulfophenyl-tetrazolium carboxanilide (XTT) reduction assay. The anti-biofilm effect of 5% PI and 0.3% PI + 0.5% H Results: PI and H Conclusions: In the case of PJI caused by Gram-positive bacteria, 0.3% PI + 0.5% H₂O₂ could be used for wound irrigation for 3 minutes of exposure. In the case of PJI with a different etiological agent or PJI with an unknown etiology, it is advisable to use 5% PI for 1 minute of exposure.

Indexed as

AntisepticsBiofilmHydrogen peroxidePeriprosthetic joint infectionPJI

Identifiers

PMID39139360
PMCPMC11320471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.