Evidence map›Paper›PMID 39139153›Full record

ArticleJournal of medical biochemistry2024

Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery.

Nikola Mladenović, Ranko Zdravković, Lazar Velicki, Vanja Drljević-Todić, Mirko Todić, Srđan Maletin, Aleksandra Mladenović, Nemanja Petrović, Bogdan Okiljević, Valentina Nikolić and 5 more

Abstract read
In one paragraph

Article in Journal of medical biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nikola MladenovićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Ranko ZdravkovićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Lazar VelickiInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Vanja Drljević-TodićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Mirko TodićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Srđan MaletinInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Aleksandra MladenovićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Nemanja PetrovićInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica.
Bogdan OkiljevićInstitute of Cardiovascular Diseases Dedinje, Belgrade.
Valentina NikolićUniversity of Nis, Faculty of Medicine, Nis.
Milan PavlovićUniversity of Nis, Faculty of Medicine, Nis.
Dane KrtinićUniversity of Nis, Faculty of Medicine, Nis.
Aleksandar NikolićUniversity of Nis, Faculty of Medicine, Nis.
Marko GmijovićUniversity of Nis, Faculty of Medicine, Nis.
Aleksandar KamenovUniversity of Nis, Faculty of Medicine, Nis.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-operative atrial fibrillation (POAF) is a frequent complication after cardiac surgery. It is associated with prolonged hospital stay, increased morbidity, mortality rate and economic costs. The aim of the study was to determine the association between the values of Galectin3 and N-terminal pro-B-type natriuretic peptide (NTproBNP) with POAF after cardiac surgery. Methods: A prospective study enrolled patients aged 18-85 years old admitted due to elective coronary artery bypass graft surgery (CABG) or CABG + aortic valve replacement. The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7. Results: The study included a total of 103 patients. POAF was registered in 45 patients. The mean age of patients in whom POAF occurred was 68.8 years, while other patients' mean age was 65.5 years (p=0.028). Patients with POAF did not differ from the group without POAF in the values of Galectin-3 and NT-proBNP preoperatively as well as on the first and seventh postoperative days. Changes in Galectin-3 levels on the first postoperative day had statistically significant value for predicting POAF (AUC=0.627 0.509-0.745 , p<0.05). Decrease in Galectin-3 level con centration on the first postoperative day over 17% increases the risk of developing AF. Conclusions: Preoperative values of Galectin-3 and NTproBNP are not associated with POAF development after cardiac surgery.

Indexed as

Cardiac surgeryGalectin-3NT-proBNPPost-operative atrial fibrillation

Identifiers

PMID39139153
PMCPMC11318046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.