Evidence map›Paper›PMID 39139049›Full record

ArticleJournal of hospital medicine2024

Simultaneously implementing pathways for improving asthma, pneumonia, and bronchiolitis care for hospitalized children: Protocol for a hybrid effectiveness-implementation, cluster-randomized trial.

Yeelen Edwards, Nancy Yang, Andrew D Auerbach, Ralph Gonzales, Charles E McCulloch, Eric E Howell, Jenna Goldstein, Sara Thompson, Sunitha V Kaiser

Abstract readClinical Trial Protocol
In one paragraph

Article in Journal of hospital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yeelen EdwardsDepartment of Pediatrics, University of California, San Francisco, California, USA.
Nancy YangDepartment of Pediatrics, University of California, San Francisco, California, USA.
Andrew D AuerbachDepartment of Medicine, University of California, San Francisco, California, USA.ORCID 0000-0001-8440-0527
Ralph GonzalesDepartment of Medicine, University of California, San Francisco, California, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.
Eric E HowellSociety of Hospital Medicine, Philadelphia, Pennsylvania, USA.
Jenna GoldsteinSociety of Hospital Medicine, Philadelphia, Pennsylvania, USA.
Sara ThompsonSociety of Hospital Medicine, Philadelphia, Pennsylvania, USA.
Sunitha V KaiserDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0002-9862-9362

Funding

The SIP Study: Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized ChildrenR33HL157804 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KAISER, SUNITHA VEMULA · 2022 to 2025
$2.3M
NHLBI NIH HHS R33 HL157804NHLBI NIH HHS R33HL157804
6 · The paper itself

Abstract

backgroundAsthma, pneumonia, and bronchiolitis are the top causes of childhood hospitalization in the United States, leading to over 350,000 hospitalizations and ≈$2 billion in costs annually. The majority of these hospitalizations occur in general/community hospitals. Poor guideline adoption by clinicians contributes to poor health outcomes for children hospitalized with these illnesses, including longer recovery time/hospital stay, higher rates of intensive care unit transfer, and increased risk of hospital readmission. A prior single-center study at a children's hospital tested a multicondition clinical pathway intervention (simultaneous implementation of multiple pathways for multiple pediatric conditions) and demonstrated improved clinician guideline adherence and patient health outcomes. This intervention has not yet been studied in community hospitals, which face unique implementation barriers.

objectiveTo study the implementation and effectiveness of a multicondition pathway intervention for children hospitalized with asthma, pneumonia, or bronchiolitis in community hospitals.

methodsWe will conduct a pragmatic, hybrid effectiveness-implementation, cluster-randomized trial in community hospitals around the United States (1:1 randomization to intervention vs. wait-list control). Our primary outcome will be the adoption of two to three evidence-based practices for each condition over a sustained period of 2 years. Secondary outcomes include hospital length of stay, ICU transfer, and readmission. DISCUSSION: This hybrid trial will lead to a comprehensive understanding of how to pragmatically and sustainably implement a multicondition pathway intervention in community hospitals and an assessment of its effects. Enrollment began in July 2022 and is projected to be completed in September 2024. Primary analysis completion is anticipated in March 2025, with reporting of results following.

Indexed as

AsthmaBronchiolitisPneumoniaChildChild, HospitalizedChild, PreschoolCritical PathwaysGuideline AdherenceHospitalizationHospitals, CommunityHumansInfantLength of StayMalePragmatic Clinical Trials as TopicQuality Improvement

Identifiers

PMID39139049
PMCPMC12118519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.