Evidence map›Paper›PMID 39138957›Full record

ArticleJournal of animal physiology and animal nutrition2025

Effects of partial or full replacement of soybean meal with urea or coated urea on intake, performance, and plasma urea concentrations in lactating dairy cows.

Rainer Rauch, Kelly Nichols, Isabela P C de Carvalho, Jean-Baptiste Daniel, Javier Martín-Tereso, Jan Dijkstra

Abstract read
In one paragraph

Article in Journal of animal physiology and animal nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Effects of FermentingAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rainer RauchTrouw Nutrition R&D, Amersfoort, The Netherlands.ORCID https://orcid.org/0000-0002-0513-0643
Kelly NicholsTrouw Nutrition R&D, Amersfoort, The Netherlands.ORCID http://orcid.org/0000-0001-6062-7460
Isabela P C de CarvalhoTrouw Nutrition R&D, Amersfoort, The Netherlands.ORCID https://orcid.org/0000-0001-5551-3960
Jean-Baptiste DanielTrouw Nutrition R&D, Amersfoort, The Netherlands.ORCID https://orcid.org/0000-0001-7627-3708
Javier Martín-TeresoTrouw Nutrition R&D, Amersfoort, The Netherlands.ORCID https://orcid.org/0000-0002-6757-4629
Jan DijkstraAnimal Nutrition Group, Wageningen University and Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0003-3728-6885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We expected mitigation of the hypophagic effects of urea (U) with a coated urea (CU) product that aimed to partially shift urea supply to the post-ruminal gastrointestinal tract. Ruminal release and post-ruminal digestibility of CU was evaluated in vitro, followed by a randomised complete block experiment (54 Holstein-Friesian cows; 177 ± 72 days in milk). Soybean meal (SBM) was partially (PR) or fully (FR) replaced on an isonitrogenous basis by beet pulp and U or CU. Urea sources were included at 12 (U-PR, CU-PR) and 19 (U-FR, CU-FR) g/kg dietary dry matter (DM). Hypophagic effects were similar for U-PR and CU-PR (-11% vs. -7%), and for U-FR and CU-FR (-13% vs. -12%) compared with SBM (average 25.8 kg DM intake/d). Compared with SBM, U-PR and CU-PR reduced yields of milk (-8%) and protein (-12%), U-PR reduced yield of fat (-9%) and fat- and protein-corrected-milk (FPCM; -9%), and CU-PR tended to reduce FPCM yield (-5%). Compared with SBM, U-FR and CU-FR respectively reduced yields of milk (-21%, -22%), protein (-25%, -26%), fat (both -14%), lactose (-20%, -21%), and FPCM (-17%, -19%), and lowered N (-15%, -12%) and feed (-8%, trend, -9%) efficiency. Human-edible protein efficiency approximately doubled with U-PR and CU-PR and approximately tripled with U-FR and CU-FR compared with SBM. Milk composition and plasma urea concentration were similar between U and CU, except for a trend for a greater plasma urea concentration with U-PR compared with CU-PR. Dry matter intake patterns differed for CU-PR compared with U-PR and for CU-FR compared with U-FR, suggesting effects of urea release rate or location on feeding behaviour. Overall, replacing SBM with U or CU reduced DM intake and milk production and affected nutrient efficiencies. Coated urea influenced DM intake pattern but did not affect total DM intake or milk production compared with U.

Indexed as

Animal FeedEatingGlycine maxLactationUreaAnimal Nutritional Physiological PhenomenaAnimalsCattleDietFemaleMilkUreaammonia toxicityhuman‐edible protein efficiencynitrogen efficiencynon‐protein nitrogenurea toxicity

Identifiers

PMID39138957
PMCPMC11731464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.