Evidence map›Paper›PMID 39138513›Full record

ArticleRadiation oncology (London, England)2024

A nomogram based on circulating CD8

Chang Yan, Guohai Yang, Chaojun Zhang, KaiHua Chen, Yongchu Sun, Zhongguo Liang, Lin Lai, Ling Li, Song Qu, Xiao-Dong Zhu

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Combined Prognostic Value ofCancer medicine · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chang Yan *Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Guohai Yang *Department of Gastrointestinal Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Chaojun ZhangDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
KaiHua ChenDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Yongchu SunDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Zhongguo LiangDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Lin LaiDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Ling LiDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Song QuDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Xiao-Dong ZhuDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China. zhuxdonggxmu@126.com.

Funding

Natural Science Foundation of Guangxi Zhuang Autonomous Region 2023GXNSFBA026012the Key Research and Development Program Project of Guangxi Zhuang Autonomous Region GuikeAB23026020
6 · The paper itself

Abstract

purposeTo explore the influence of circulating lymphocyte subsets, serum markers, clinical factors, and their impact on overall survival (OS) in locally advanced nasopharyngeal carcinoma (LA-NPC). Additionally, to construct a nomogram predicting OS for LA-NPC patients using independent prognostic factors.

methodsA total of 530 patients with LA-NPC were included in this study. In the training cohort, Cox regression analysis was utilized to identify independent prognostic factors, which were then integrated into the nomogram. The concordance index (C-index) was calculated for both training and validation cohorts. Schoenfeld residual analysis, calibration curves, and decision curve analysis (DCA) were employed to evaluate the nomogram. Kaplan-Meier methods was performed based on risk stratification using the nomogram.

resultsA total of 530 LA-NPC patients were included. Multivariate Cox regression analysis revealed that the circulating CD8

conclusionCirculating CD8

Indexed as

CD8-Positive T-LymphocytesNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNomogramsAdultAgedBlood PlateletsFemaleHumansLymphocytesMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateYoung AdultCD8+ T cellImmune functionInflammatory markersNasopharyngeal carcinomaPrognosis

Identifiers

PMID39138513
PMCPMC11323451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.