Evidence map›Paper›PMID 39138457›Full record

ArticleBMC public health2024

Causes of pre and post-donation deferrals among blood donors, at Kwale Satellite Blood Transfusion Center, Kwale County, Kenya, 2018-2022.

Gibson Waweru Nyamu, Matano Ali Shee, Polly Kiende, Benson Muithya Muthiani, Rocky Jumapili Nakazea, Narcis Mwakidedela Mwasowa, Frendrick Odhiambo, Jacintah Mueni King'oo, Ronald Nyarambe Wigina

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Gibson Waweru NyamuMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya. wawerugibson2015@gmail.com.
Matano Ali SheeSchool of Applied and Health Sciences, Department of Medical Sciences, Technical University of Mombasa, P.O Box 90420,-80100, Mombasa, Kenya.
Polly KiendeMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Benson Muithya MuthianiMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Rocky Jumapili NakazeaMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Narcis Mwakidedela MwasowaMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Frendrick OdhiamboMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Jacintah Mueni King'ooMinistry of Health, P.O. Box: 30016-00100, Nairobi, Kenya.
Ronald Nyarambe WiginaSchool of Applied and Health Sciences, Department of Medical Sciences, Technical University of Mombasa, P.O Box 90420,-80100, Mombasa, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth pre-donation and post-donation deferrals pose challenges to blood safety and availability. This study delved into the deferral rates before donations and their underlying reasons, as, transfusion transmissible infections (TTIs) leading to post-donation deferrals among potential blood donors at the Kwale Satellite Blood Transfusion Centre (KSBTC) in Kenya.

methodsWe performed a retrospective electronic record review of pre- and post-donation deferrals among blood donors at KSBTC, 2018-2022. The pre-donations deferral rate and reasons for deferral were analyzed. Accepted donations were analyzed to determine the prevalence of HIV, hepatitis B (HBV), hepatitis C (HCV), and syphilis. Descriptive statistics were calculated and both crude odds ratio (COR) and adjusted odds ratio (AOR), and their 95% confidence intervals (CI) were calculated. Variables with p < 0.05 were considered statistically significant.

resultsA review was conducted on 12,633 blood donation records. Among these, individuals 2,729/12,633 (21.60%) were deferred from donating with the primary reason being low hemoglobin levels, constituting 51.86% of deferrals. Around 773/9,904 (7.80%) of blood units, were discarded due to at least one TTI. Among these, HBV accounted for 4.73%, HIV for 2.01%, HCV for 1.21%, and Syphilis for 0.59% of cases. The adjusted odds ratio for male donors were, (aOR = 1.3, 95% CI 1.01-1.57), donors with none or primary education level (aOR = 1.4 95% CI 1.11-1.68), first-timer donors (aOR = 1.2, 95% CI 1.01-1.44), and static strategy for blood collection (aOR = 1.4, 95%CI 1.12-1.63) were independently potentially associated with testing positive for at least one TTI.

conclusionThe study indicates that TTIs continue to pose a risk to the safety of Kenya's bloodstock, with a notable prevalence of HBV infections. Male donors, individuals with limited education, first-time donors, and utilizing a fixed strategy for blood collection were identified as potential risk factors independently associated with TTIs.

Indexed as

Blood DonorsAdolescentAdultDonor SelectionFemaleHepatitis BHepatitis CHIV InfectionsHumansKenyaMaleMiddle AgedPrevalenceRetrospective StudiesSyphilisYoung AdultBlood donation deferralsBlood donorsHepatitis BHepatitis CHIVSyphilisTransfusion transmissible infections

Identifiers

PMID39138457
PMCPMC11321081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.