Evidence map›Paper›PMID 39138250›Full record

ArticleScientific reports2024

Lipid production from corn straw by cellobiohydrolase and delta-6 desaturase engineered Mucor circinelloides strains under solid state fermentation.

Yao Zhang, Zhuo Liu, Yan Sun, Yuanxin Du, Zixuan Zhao, Qing Liu, Yuanda Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yao ZhangFood Bioengineering and Technology Laboratory, Department of Food Science and Nutrition, College of Culture and Tourism, University of Jinan, 13 Shungeng Road, Jinan, 250022, People's Republic of China. shc_zhangy@ujn.edu.cn.
Zhuo LiuFood Bioengineering and Technology Laboratory, Department of Food Science and Nutrition, College of Culture and Tourism, University of Jinan, 13 Shungeng Road, Jinan, 250022, People's Republic of China.
Yan SunFood Bioengineering and Technology Laboratory, Department of Food Science and Nutrition, College of Culture and Tourism, University of Jinan, 13 Shungeng Road, Jinan, 250022, People's Republic of China.
Yuanxin DuFood Bioengineering and Technology Laboratory, Department of Food Science and Nutrition, College of Culture and Tourism, University of Jinan, 13 Shungeng Road, Jinan, 250022, People's Republic of China.
Zixuan ZhaoFood Bioengineering and Technology Laboratory, Department of Food Science and Nutrition, College of Culture and Tourism, University of Jinan, 13 Shungeng Road, Jinan, 250022, People's Republic of China.
Qing LiuSchool of Agricultural Engineering and Food Science, Colin Ratledge Center for Microbial Lipids, Shandong University of Technology, 266 Xincun West Road, Zibo, 255000, People's Republic of China.
Yuanda SongSchool of Agricultural Engineering and Food Science, Colin Ratledge Center for Microbial Lipids, Shandong University of Technology, 266 Xincun West Road, Zibo, 255000, People's Republic of China.

Funding

National Natural Science Foundation of China 32101927School-City integration project in Zhangdian District 2021JSCG0016Shandong Provincial Natural Science Foundation ZR2020MC007
6 · The paper itself

Abstract

Previously, we constructed engineered M. circinelloides strains that can not only utilize cellulose, but also increase the yield of γ-linolenic acid (GLA). In the present study, an in-depth analysis of lipid accumulation by engineered M. circinelloides strains using corn straw was to be explored. When a two-stage temperature control strategy was adopted with adding 1.5% cellulase and 15% inoculum, the engineered strains led to increases in the lipid yield (up to 1.56 g per 100 g dry medium) and GLA yield (up to 274 mg per 100 g dry medium) of 1.8- and 2.3-fold, respectively, compared with the control strain. This study proved the engineered M. circinelloides strains, especially for Mc-C2PD6, possess advantages in using corn straw to produce GLA. This work provided a reference for transformation from agricultural cellulosic waste to functional lipid in one step, which might play a positive role in promoting the sustainable development of biological industry.

Indexed as

Cellulose 1,4-beta-CellobiosidaseFermentationMucorZea maysCelluloseFatty Acid Desaturasesgamma-Linolenic AcidLipid MetabolismLipidsMetabolic EngineeringCelluloseCellulose 1,4-beta-CellobiosidaseFatty Acid Desaturasesgamma-Linolenic AcidLipidsCelluloseCorn strawLipidMucor circinelloidesγ-Linolenic acid

Identifiers

PMID39138250
PMCPMC11322153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.