ArticleNature communications2024
Synergistic pectin deconstruction is a prerequisite for mutualistic interactions between honeybee gut bacteria.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut.PLoS biology · 2026Article
- Tracking Microbiome Composition and Stability Across Indian Social Honeybees Foraging in a Homogeneous Mustard Crop Landscape.Microbial ecology · 2026Article
- Synthetic Microbial Community Biosensors: From Engineered Ecosystems to Modular Detection Platforms with AI-Driven Intelligence.Biosensors · 2026Review
- Gut Symbiont-Driven Adaptive Evolution of Herbivorous Insect-Plant Interactions and Its Ecological Implications.Plants (Basel, Switzerland) · 2025Review
- Gut microbiota profiling of Apis cerana indica across biodiversity hotspots in the Western Ghats, India.Molecular biology reports · 2025Article
- Honeybee-Gilliamella synergy in carbohydrate metabolism enhances host thermogenesis in cold acclimation.NPJ biofilms and microbiomes · 2025Article
- Effects of Three Different Bee Pollen on Digestion, Immunity, Antioxidant Capacity, and Gut Microbes inInsects · 2025Article
- Life history strategies complement niche partitioning to support the coexistence of closely related Gilliamella species in the bee gut.The ISME journal · 2025Article
- Microorganism changes in the gut ofFrontiers in cellular and infection microbiology · 2025Article
- Dietary Conversion from All-Concentrate to All-Roughage Alters Rumen Bacterial Community Composition and Function in Yak, Cattle-Yak, Tibetan Yellow Cattle and Yellow Cattle.Animals : an open access journal from MDPI · 2024Article
- Synergistic pectin deconstruction is a prerequisite for mutualistic interactions between honeybee gut bacteria.Nature communications · 2024Article
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Authors and funding
9 authors.
Funding
Abstract
The honeybee gut microbiome is crucial for degrading diverse pollen glycans. Yet it is unclear how this process shapes the interactions among bacteria. Here, we demonstrate a conditional mutualistic interaction between strains of two honeybee gut bacteria Bifidobacterium asteroides and Gilliamella apicola. When co-occurring in vitro and in vivo, Bifidobacterium provides complementary demethylation service to promote Gilliamella growth on methylated homogalacturonan, an enriched polysaccharide of pectin. In exchange, Gilliamella shares digestive products with Bifidobacterium, through which a positive interaction is established. This positive interaction vanishes when Bifidobacterium is not required on a non-methylated diet. Results from biochemical and gene expression analyses combined with model simulation further suggest that the ratio change of the two major homogalacturonan breakdown products, galacturonic acid (GalA) and di-GalA, determines the bacterial interaction. This study unravels how glycan metabolism may shape the interactions between honeybee gut bacteria.
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