Evidence map›Paper›PMID 39138095›Full record

ReviewThe Lancet. Digital health2024

Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world.

L Nelson Sanchez-Pinto, María Del Pilar Arias López, Halden Scott, Kristen Gibbons, Michael Moor, R Scott Watson, Matthew O Wiens, Luregn J Schlapbach, Tellen D Bennett

Abstract readReview
In one paragraph

Review in The Lancet. Digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
    Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L Nelson Sanchez-PintoDepartment of Pediatrics, Northwestern University Feinberg School of Medicine and Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA. Electronic address: lsanchezpinto@luriechildrens.org.
María Del Pilar Arias LópezChildren's Hospital Ricardo Gutierrez, SATI-Q Program, Buenos Aires, Argentina.
Halden ScottDepartment of Pediatrics, University of Colorado-Denver and Children's Hospital Colorado, Aurora, CO, USA.
Kristen GibbonsChildren's Intensive Care Research Program, Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.
Michael MoorDepartment of Computer Science, Stanford University, Stanford, CA, USA.
R Scott WatsonDepartment of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA, USA.
Matthew O WiensDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada; World Alliance for Lung and Intensive Care Medicine in Uganda, Kampala, Uganda.
Luregn J SchlapbachChildren's Intensive Care Research Program, Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia; Department of Intensive Care and Neonatology, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Tellen D BennettDepartment of Pediatrics, University of Colorado-Denver and Children's Hospital Colorado, Aurora, CO, USA.

Funding

SHIPSS: Stress Hydrocortisone In Pediatric Septic ShockR01HD096901 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI AGUS, MICHAEL SD, WYPIJ, DAVID · 2019 to 2024
$8.9M
Pediatric COVID-19 Severity Dashboard During Delta Variant CirculationR01HD105939 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Tellen Bennett, Lazaro Nelson Sanchez-Pinto · 2021 to 2026
$4.6M
Pediatric Sepsis Biorepository and Clinical DatabaseR33GM146159 · NIGMS · CHILDREN'S HOSP OF PHILADELPHIA · PI BALAMUTH, FRANCES B, SANCHEZ-PINTO, LAZARO NELSON · 2024 to 2025
$1.4M
Phenotype prediction and therapeutic targets in high-risk pediatric sepsis-associated MODSR01HD113695 · NICHD · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI Lazaro Nelson Sanchez-Pinto · 2024 to 2026
$1.2M
Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotypingR21GM151703 · NIGMS · CINCINNATI CHILDRENS HOSP MED CTR · PI ATREYA, MIHIR R, KAMALESWARAN, RISHIKESAN · 2023 to 2024
$459k
NICHD NIH HHS R01 HD096901NICHD NIH HHS R01 HD105939NICHD NIH HHS R01 HD113695NIGMS NIH HHS R21 GM151703NIGMS NIH HHS R33 GM146159
6 · The paper itself

Abstract

The digitisation of health care is offering the promise of transforming the management of paediatric sepsis, which is a major source of morbidity and mortality in children worldwide. Digital technology is already making an impact in paediatric sepsis, but is almost exclusively benefiting patients in high-resource health-care settings. However, digital tools can be highly scalable and cost-effective, and-with the right planning-have the potential to reduce global health disparities. Novel digital solutions, from wearable devices and mobile apps, to electronic health record-embedded decision support tools, have an unprecedented opportunity to transform paediatric sepsis research and care. In this Series paper, we describe the current state of digital solutions in paediatric sepsis around the world, the advances in digital technology that are enabling the development of novel applications, and the potential effect of advances in artificial intelligence in paediatric sepsis research and clinical care.

Indexed as

SepsisArtificial IntelligenceChildDigital TechnologyElectronic Health RecordsGlobal HealthHumansMobile ApplicationsPediatricsWearable Electronic Devices

Identifiers

PMID39138095
PMCPMC11371309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.