ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2024
Cancer incidence following bariatric surgery in renal transplant recipients: a retrospective multi-center analysis.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Review
- Association Between Metabolic and Bariatric Surgery and Melanoma Risk: A Systematic Review and Meta-analysis of Observational Studies.Obesity surgery · 2026Review
- Beyond Single-Score Matching: A Two-Dimensional Propensity Score Method for Mixed Covariate Types.Research square · 2026Article
- The Weight of a New Heart: Bariatric Surgery after Heart Transplantation and its Clinical Impact.Obesity surgery · 2026Article
- EHRchitect: An open-source software tool for medical event sequences data extraction from Electronic Health Records.Journal of clinical and translational science · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundObesity, a known independent risk factor for developing malignancy. Additionally, renal transplant recipients (RTR) confer a 2- to 4-fold increased risk of overall malignancies with an excess absolute risk of .7% per year. While transplant recipients are at risk for obesity and malignancy, the effect of bariatric surgery (BS) in the posttransplantation setting is not well known.
objectivesOur study primarily evaluated the impact of BS on cancer incidence in RTR with severe obesity in the posttransplantation setting. Weight loss outcomes were analyzed secondarily.
settingUniversity Hospital.
methodsA retrospective study using TriNetX database was developed to analyze cancer outcomes in RTR with posttransplantation BS versus RTR without BS from 2000 to 2023. After the exclusion process and propensity matching, both cohorts consisted of 153 patients.
resultsRTR-BS had a significantly lower incidence of overall cancer and transplant-related cancers (P < .05). No significant difference was identified in cutaneous, gastrointestinal, and reproductive cancers. Percent Excess Weight Loss (%EWL) was significantly lower in RTR-only cohort (11.4%) versus RTR-BS cohort (57.8%) at 5 years. Sleeve gastrectomy (SG) patients (73.19%) had significantly higher %EWL than Roux en-Y gastric bypass (RYGB) patients (49.33%) at 3 years. No difference in cancer incidence was noted between SG and RYGB patients.
conclusionPostrenal transplantation BS had a diminishing effect on overall and transplant-related cancer incidence in RTR with severe obesity. Significant weight loss was also demonstrated with post-renal transplantation BS.
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