Evidence map›Paper›PMID 39137988›Full record

ArticleeNeuro2024

Transsynaptic BMP Signaling Regulates Fine-Scale Topography between Adjacent Sensory Neurons.

Takuya Kaneko, Ruonan Li, Qun He, Limin Yang, Bing Ye

Abstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Journal of biological rhythms · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takuya KanekoLife Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.
Ruonan LiLife Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.
Qun HeSchool of Medicine, Dalian University, Dalian 116622, China.
Limin YangSchool of Medicine, Dalian University, Dalian 116622, China bingye@umich.edu yanglimin@dlu.edu.cn.ORCID https://orcid.org/0000-0002-1352-4263
Bing YeLife Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109 bingye@umich.edu yanglimin@dlu.edu.cn.ORCID https://orcid.org/0000-0002-8828-4065

Funding

Mechanisms that differentiate dendrite development from axon developmentR01MH112669 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YE, BING · 2017 to 2021
$1.9M
The assembly of population coding networksR01NS128500 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TZUMIN LEE · 2023 to 2026
$1.5M
NIMH NIH HHS R01 MH112669NINDS NIH HHS R01 NS128500
6 · The paper itself

Abstract

Sensory axons projecting to the central nervous system are organized into topographic maps that represent the locations of sensory stimuli. In some sensory systems, even adjacent sensory axons are arranged topographically, forming "fine-scale" topographic maps. Although several broad molecular gradients are known to instruct coarse topography, we know little about the molecular signaling that regulates fine-scale topography at the level of two adjacent axons. Here, we provide evidence that transsynaptic bone morphogenetic protein (BMP) signaling mediates local interneuronal communication to regulate fine-scale topography in the nociceptive system of

Indexed as

Bone Morphogenetic ProteinsDrosophila ProteinsSensory Receptor CellsSignal TransductionAnimalsAnimals, Genetically ModifiedDNA-Binding ProteinsDrosophilaLarvaNociceptorsPresynaptic TerminalsSynapsesTranscription FactorsBone Morphogenetic ProteinsDNA-Binding Proteinsdpp protein, DrosophilaDrosophila ProteinsMAD protein, DrosophilaTranscription FactorsaxonBMP signalingDrosophilasensorytopography

Identifiers

PMID39137988
PMCPMC11360983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.