Evidence map›Paper›PMID 39137897›Full record

ArticleNature2024

Amplification of autoimmune organ damage by NKp46-activated ILC1s.

Stylianos-Iason Biniaris-Georgallis, Tom Aschman, Katerina Stergioula, Frauke Schreiber, Vajiheh Jafari, Anna Taranko, Tejal Karmalkar, Ana Kasapi, Tihana Lenac Rovis, Vedrana Jelencic and 30 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. A population-scale atlas of blood and tissue in lupus nephritis.bioRxiv : the preprint server for biology · 2026
    Article
  8. Cell-cell crosstalk in kidney health and disease.Nature reviews. Nephrology · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Lupus nephritis.Nature reviews. Disease primers · 2025
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

40 authors.

Stylianos-Iason Biniaris-Georgallis *Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Tom Aschman *Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.ORCID 0000-0002-2101-6146
Katerina Stergioula *Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Frauke SchreiberDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Vajiheh JafariDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Anna TarankoDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.ORCID 0000-0002-2660-7762
Tejal KarmalkarDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Ana KasapiDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Tihana Lenac RovisCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Vedrana JelencicCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
David A BejaranoQuantitative Systems Biology, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Lea FabryDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
Michail PapacharalampousDepartment of Rheumatology and Clinical Immunology, Medical Center -University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Irene MattiolaGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.ORCID 0000-0002-2922-9947
Martina MolgoraDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Jinchao HouDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Karolin W HublitzInstitute of Microbiology, Infectious Diseases and Immunology (I-MIDI), Charité-Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Germany.ORCID 0000-0003-4840-4496
Frederik HeinrichGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.
Gabriela Maria GuerraGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.
Pawel DurekGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.
Giannino PatoneCardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.ORCID 0000-0002-7242-0341
Eric L LindbergCardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.ORCID 0000-0002-2979-433X
Henrike MaatzCardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Oliver HölskenGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.ORCID 0000-0001-6086-9275
Gerhard KrönkeDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.ORCID 0000-0002-7566-4325
Arthur MorthaDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-2673-0485
Reinhard E VollDepartment of Rheumatology and Clinical Immunology, Medical Center -University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-5542-9133
Alexander J ClarkeKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.ORCID 0000-0003-2846-7860
Anja E HauserDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.ORCID 0000-0002-7725-9526
Marco ColonnaDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0001-5222-4987
Kevin ThurleyGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.
Andreas SchlitzerQuantitative Systems Biology, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID 0000-0001-7662-3712
Christoph SchneiderInstitute of Physiology, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-0452-2960
Efstathios G StamatiadesInstitute of Microbiology, Infectious Diseases and Immunology (I-MIDI), Charité-Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Germany.ORCID 0000-0002-2785-9005
Mir-Farzin MashreghiGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany.ORCID 0000-0002-8015-6907
Stipan JonjicCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.ORCID 0000-0001-5003-3108
Norbert HübnerCardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.ORCID 0000-0002-1218-6223
Andreas DiefenbachGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, Berlin, Germany. andreas.diefenbach@charite.de.ORCID 0000-0002-9176-9530
Masatoshi KandaCardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany. mkanda@sapmed.ac.jp.ORCID 0000-0003-3468-3586
Antigoni TriantafyllopoulouDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin Campus Mitte, Berlin, Germany. antigoni.triantafyllopoulou@charite.de.ORCID 0000-0003-0123-7117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In systemic lupus erythematosus, loss of immune tolerance, autoantibody production and immune complex deposition are required but not sufficient for organ damage

Indexed as

AutoimmunityImmunity, InnateKidneyLupus NephritisLymphocytesNatural Cytotoxicity Triggering Receptor 1Parenchymal TissueAnimalsAntigens, LyAutoantibodiesEpithelial CellsFemaleGranulocyte-Macrophage Colony-Stimulating FactorHumansMacrophagesMiceAntigens, LyAutoantibodiesGranulocyte-Macrophage Colony-Stimulating FactorNatural Cytotoxicity Triggering Receptor 1NCR1 protein, humanNcr1 protein, mouse

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.