Evidence map›Paper›PMID 39137690›Full record

ArticleJournal of critical care2024

Normalization of IL-6 levels is associated with survival in critically ill patients with COVID-19.

Anahita Mostaghim, Neha A Sathe, F Linzee Mabrey, Sharon Sahi, Nick O'Connor, Eric D Morrell, Michael Fitzpatrick, Craig H Smith, Mark M Wurfel, W Conrad Liles and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anahita MostaghimDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD, USA. Electronic address: anahita.mostaghim@gmail.com.
Neha A SatheDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
F Linzee MabreyDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Sharon SahiDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Nick O'ConnorDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Eric D MorrellDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA; Sepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA.
Michael FitzpatrickSepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA.
Craig H SmithSepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA.
Mark M WurfelDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA; Sepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA.
W Conrad LilesDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA; Sepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA.
Pavan K BhatrajuDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA; Sepsis Center of Research Excellence, University of Washington (SCORE-UW), Seattle, WA, USA; Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA, USA.

Funding

Identification and Validation of Biological Sub-phenotypes of Sepsis-induced Acute Kidney Injury: A Precision Medicine Approach to Improve Clinical OutcomesR01DK133177 · NIDDK · UNIVERSITY OF WASHINGTON · PI Pavan Kumar Bhatraju · 2022 to 2026
$2.6M
Targeting CD14: A Novel Therapeutic Approach for Acute Respiratory Distress SyndromeK23HL175255 · NHLBI · UNIVERSITY OF WASHINGTON · PI Frances Linzee Mabrey · 2024 to 2026
$559k
NHLBI NIH HHS K23 HL175255NIDDK NIH HHS R01 DK133177
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Critical IllnessInterleukin-6SARS-CoV-2AgedBiomarkersFemaleHumansIntensive Care UnitsMaleMiddle AgedBiomarkersInterleukin-6AKICOVID-19ICUIL-6Mortality

Identifiers

PMID39137690
PMCPMC12180609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.