Evidence map›Paper›PMID 39137414›Full record

ArticleJMIR research protocols2024

Improving the Well-Being of People With Advanced Cancer and Their Family Caregivers: Protocol for an Effectiveness-Implementation Trial of a Dyadic Digital Health Intervention (FOCUSau).

Peter Hudson, Jill Francis, Joachim Cohen, Suzanne Kapp, Richard De Abreu Lourenco, Lisa Beatty, Kathleen Gray, Michael Jefford, Ilona Juraskova, Laurel Northouse and 7 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR research protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06082128 (Improving the Wellbeing of People With Advanced Cancer and Their Family Carers), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06082128 naunknown statusnot on this map

Improving the Wellbeing of People With Advanced Cancer and Their Family Carers: An Effectiveness Implementation Trial of an Australian Dyadic Digital Health Intervention (FOCUSau)

TypeinterventionalSponsorUniversity of MelbourneRan2023 to 2025Enrolled433ConditionsAdvanced CancerArmsFOCUSau
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Peter HudsonCentre for Palliative Care, c/o St Vincent's Hospital and The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-5891-8197
Jill FrancisMelbourne School of Health Sciences, The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-5784-8895
Joachim CohenEnd of Life Care Research Group, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-7224-9476
Suzanne KappMelbourne School of Health Sciences, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-5438-8384
Richard De Abreu LourencoCentre for Health Economics Research and Evaluation (CHERE), University of Technology Sydney, Sydney, Australia.ORCID 0000-0002-5978-8774
Lisa BeattyCollege of Education, Psychology and Social Work, Flinders Institute for Mental Health and Wellbeing, Flinders University, Adelaide, Australia.ORCID 0000-0001-8847-8452
Kathleen GrayCentre for Digital Transformation of Health, The University of Melbourne, Melbourne, Australia.ORCID 0000-0003-1616-2170
Michael JeffordSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-8792-7807
Ilona JuraskovaFaculty of Science, School of Psychology, University of Sydney, Sydney, Australia.ORCID 0000-0001-9396-4113
Laurel NorthouseSchool of Nursing, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0002-2567-2183
Aline de VleminckEnd of Life Care Research Group, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-3321-9311
Sungwon ChangFaculty of Health, Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), University of Technology Sydney, Sydney, Australia.ORCID 0000-0003-0723-3192
Patsy YatesCancer and Palliative Care Outcomes Centre, Queensland University of Technology, Queensland, Australia.ORCID 0000-0001-8946-8504
Sophy AthanCancer Consumer Advisory Committee, Victorian Comprehensive Cancer Centre Alliance, Melbourne, Australia.ORCID 0009-0003-2547-3824
Shaira BaptistaMelbourne School of Health Sciences, The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-9474-3590
Marlena KlaicMelbourne School of Health Sciences, The University of Melbourne, Melbourne, Australia.ORCID 0000-0003-2328-0503
Jennifer PhilipSt. Vincent's Hospital and the Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-3312-0645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced cancer significantly impacts patients' and family caregivers' quality of life. When patients and caregivers are supported concurrently as a dyad, the well-being of each person is optimized. Family, Outlook, Communication, Uncertainty, Symptom management (FOCUS) is a dyadic, psychoeducational intervention developed in the United States, shown to improve the well-being and quality of life of patients with advanced cancer and their primary caregivers. Originally, a nurse-delivered in-person intervention, FOCUS has been adapted into a self-administered web-based intervention for European delivery.

objectiveThe aims of this study are to (1) adapt FOCUS to the Australian context (FOCUSau); (2) evaluate the effectiveness of FOCUSau in improving the emotional well-being and self-efficacy of patients with advanced cancer and their primary caregiver relative to usual care control group; (3) compare health care use between the intervention and control groups; and (4) assess the acceptability, feasibility, and scalability of FOCUSau in order to inform future maintainable implementation of the intervention within the Australian health care system.

methodsFOCUS will be adapted prior to trial commencement, using an iterative stakeholder feedback process to create FOCUSau. To examine the efficacy and cost-effectiveness of FOCUSau and assess its acceptability, feasibility, and scalability, we will undertake a hybrid type 1 implementation study consisting of a phase 3 (clinical effectiveness) trial along with an observational implementation study. Participants will include patients with cancer who are older than 18 years, able to access the internet, and able to identify a primary support person or caregiver who can also be approached for participation. The sample size consists of 173 dyads in each arm (ie, 346 dyads in total). Patient-caregiver dyad data will be collected at 3 time points-baseline (T

resultsThe study was funded in March 2022. Recruitment commenced in July 2024.

conclusionsIf shown to be effective, this intervention will improve the well-being of patients with advanced cancer and their family caregivers, regardless of their location or current level of health care support.

trial registrationClinicalTrials.gov NCT06082128; https://clinicaltrials.gov/study/NCT06082128. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/55252.

Indexed as

CaregiversNeoplasmsQuality of LifeAustraliaDigital HealthFemaleHumansMaleMiddle Agedadvanced cancerAustraliaAustraliancancercaregivercaregiversclinical trialcost-effectivenessdigital healthdigital health interventiondyadefficacyfamily caregiverfamily caregivershealth economicsimplementation sciencepalliative carepsychoeducationquality of lifeself-administeredweb-basedweb-based interventionwell-beingwellbeing

Identifiers

PMID39137414
PMCPMC11350297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.