ArticleThe Journal of cardiovascular nursing
Association of Heart Failure With Cognitive Decline and Development of Mild Cognitive Impairment and Dementia.
Article in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Assessment of cognitive function in patients with heart failure: impact of clinical and sociodemographic factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Trajectory of cognitive decline before and after incident heart failure among older adults: A 20-Year, population-based, prospective cohort study.The journal of prevention of Alzheimer's disease · 2026Article
- Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure.Frontiers in medicine · 2026Article
- The heart-brain axis: neurocognitive frailty in heart failure.Journal of neurology · 2025Review
- Uncovering Proteins Commonly Expressed Between Heart Failure and Dementia Using Bioinformatic Tools.Current issues in molecular biology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundIncidence of cognitive impairment and its consequences have not been fully examined in heart failure (HF).
objectiveThe aim of this study was to examine associations of HF with cognitive decline, frequencies and risks of, and time-to-develop mild cognitive impairment (MCI) or dementia during 15-year follow-up.
methodsFor this retrospective cohort study, data were retrieved from the National Alzheimer's Coordinating Center. Cognitive decline was assessed using the Uniform Data Set neuropsychological battery. Development of MCI and dementia was assessed using clinically diagnosed cognitive status.
resultsCompared with participants without HF (n = 12 904), participants with HF (n = 256) had more decline in attention, executive function, and memory while controlling for covariates including apolipoprotein E4. Participants with HF developed MCI or dementia more frequently (44.9% vs 34.4%), developed dementia faster from normal cognition, and had a lower risk of dementia from MCI after controlling for covariates (hazard ratio, 0.71) than participants without HF.
conclusionsHeart failure was associated with accelerated cognitive decline.
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