Evidence map›Paper›PMID 39137127›Full record

ArticleBiochemistry2024

Harrison C Greenberg, Ananya Majumdar, Ekroop Kaur Cheema, Anton Kozyryev, Steven E Rokita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harrison C GreenbergChemistry-Biology Interface Graduate Training Program, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.
Ananya MajumdarBiomolecular NMR Center, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.
Ekroop Kaur CheemaDepartment of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.
Anton KozyryevDepartment of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.
Steven E RokitaChemistry-Biology Interface Graduate Training Program, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.ORCID 0000-0002-2292-2917

Funding

The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM080189 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2008 to 2022
$3.5M
The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM149382 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI STEVEN E ROKITA · 2023 to 2026
$1.4M
Switching Between One and Two Electron Mechanisms in the Nitroreductase SuperfamilyR01GM130937 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM130937NIGMS NIH HHS T32 GM080189NIGMS NIH HHS T32 GM149382
6 · The paper itself

Abstract

Active site lids are common features of enzymes and typically undergo conformational changes upon substrate binding to promote catalysis. Iodotyrosine deiodinase is no exception and contains a lid segment in all of its homologues from human to bacteria. The solution-state dynamics of the lid have now been characterized using

Indexed as

Catalytic DomainIodide PeroxidaseCrystallography, X-RayFluorineHumansKineticsLigandsModels, MolecularNuclear Magnetic Resonance, BiomolecularProtein BindingProtein ConformationSubstrate SpecificityFluorineIodide PeroxidaseLigands

Identifiers

PMID39137127
PMCPMC11371475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.