Evidence map›Paper›PMID 39136738›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Properties and medical applications of the Euphorbiaceae family and their bioproducts: a patent review.

Laila Maria Barreto Silva, Rodrigo Cunha Oliveira, Dianne Dominguez Formoso, Marta Bruno Loureiro, Luzimar Gonzaga Fernandez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Ingenane Diterpenoids fromMolecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laila Maria Barreto SilvaBiochemistry and Biophysics Department, Federal University of Bahia, Salvador, Brazil.
Rodrigo Cunha OliveiraBiochemistry and Biophysics Department, Federal University of Bahia, Salvador, Brazil.
Dianne Dominguez FormosoDepartment of Natural Products Chemistry, Federal University of São Carlos, São Paulo, São Carlos, Brazil.
Marta Bruno LoureiroBiochemistry and Biophysics Department, Federal University of Bahia, Salvador, Brazil.
Luzimar Gonzaga FernandezBiochemistry and Biophysics Department, Federal University of Bahia, Salvador, Brazil. luzimargonzaga@gmail.com.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq - Brazilian Ministry of Science and Technology), and the Universidade Federal da Bahia PROPCI/PROPG-PIBIC 2023-2024Fundação de Amparo à Pesquisa do Estado da Bahia FAPESB, Grants DCR Nº 0016/2023
6 · The paper itself

Abstract

Euphorbiaceae is a family of dicotyledonous angiosperm plants that occur mainly in the tropics and produce a variety of secondary metabolites. Given the abundance of the Euphorbiaceae species and the diversity of substances they produce, this study aims to investigate paten documents concerning inventions and models involving the pharmacological use of these species, contributing to the study of their medicinal potential. The present review delves into patent documents in the Patentscope database, from the application of search criteria, such as "simple search" with the "Euphorbiaceae" keyword, limited to the front page, with stemming, without language limitation, from any patent office, and excluding non-patent literature (NPL). The selected patents were prevalently published in East Asian offices between 1998 and 2023, including 41 species of Euphorbiaceae of 19 genera, with 31 metabolites represented. The collected metabolites predominantly exhibited anti-tumoral (N = 21), anti-inflammatory (N = 10), antioxidant (N = 7), and anti-bacterial (N = 6) activities. Additionally, some substances have shown valid properties for treating non-communicable diseases (N = 8). The patents demonstrate the biotechnological potential of species from the Euphorbiaceae family, which are exceptionally satile regarding their applications in the health sector. However, the small number of patents that identify specific metabolites hinders a more thorough investigation of the activities of the products extracted from these species.

Indexed as

EuphorbiaceaePlant ExtractsAnimalsHumansPatents as TopicPlant ExtractsMetabolitesNatural productsPharmacological potentialToxic substances

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.