Evidence map›Paper›PMID 39135942›Full record

ArticleClinical kidney journal2024

National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study.

Elizabeth Colby, Samantha Hayward, Melissa Benavente, Fiona Robertson, Agnieszka Bierzynska, Amy Osborne, Kevon Parmesar, Maryam Afzal, Tracey Chapman, Fatima Ullah and 16 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. From data to drug: the translational impact of RaDaR, the UK national registry of rare kidney diseases.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  3. Article
  4. Article
  5. Long-Term Outcomes in Nephrotic Syndrome by Kidney Biopsy Diagnosis and Proteinuria.Journal of the American Society of Nephrology : JASN · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Elizabeth ColbyBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Samantha HaywardBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-3234-7549
Melissa BenaventeCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Fiona RobertsonCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Agnieszka BierzynskaBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Amy OsborneBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Kevon ParmesarBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Maryam AfzalBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Tracey ChapmanBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Fatima UllahBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Elaine DaviesKidney Research UK, Peterborough, UK.
Michael NationKidney Research UK, Peterborough, UK.
Wendy CookNephrotic Syndrome Trust, Somerset, UK.
Tim JohnsonExperimental Renal Medicine, Medical School, University of Sheffield, Sheffield, UK.
Uwe AndagMetabolic Disease and Bioinformatics, Evotec International GmbH, Hamburg, Germany.
Olivier RadresaMetabolic Disease and Bioinformatics, Evotec International GmbH, Hamburg, Germany.
Philipp SkroblinMetabolic Disease and Bioinformatics, Evotec International GmbH, Hamburg, Germany.
Michaela BayerlovaMetabolic Disease and Bioinformatics, Evotec International GmbH, Hamburg, Germany.
Robert UnwinResearch and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Nicolas VuilleumierDivision of Laboratory Medicine, Diagnostics Department and Department of Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Rosamonde E BanksLeeds Institute of Medical Research at St James's, School of Medicine, University of Leeds, Leeds, UK (now Emerita position).
Fiona BraddonUK Renal Registry, Bristol, UK.
Ania KoziellDepartment of Experimental Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Maarten W TaalCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0002-9065-212X
Gavin I WelshBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Moin A SaleemBristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Idiopathic nephrotic syndrome (INS) is a heterogenous disease and current classification is based on observational responses to therapies or kidney histology. The National Unified Renal Translational Research Enterprise (NURTuRE)-INS cohort aims to facilitate novel ways of stratifying INS patients to improve disease understanding, therapeutics and design of clinical trials. Methods: NURTuRE-INS is a prospective cohort study of children and adults with INS in a linked biorepository. All recruits had at least one sampling visit collecting serum, plasma, urine and blood for RNA and DNA extraction, frozen within 2 hours of collection. Clinical histology slides and biopsy tissue blocks were also collected. Results: A total of 739 participants were recruited from 23 centres to NURTuRE-INS, half of whom were diagnosed in childhood [ Conclusions: NURTuRE-INS is a prospective cohort study with high-quality biosamples and longitudinal data that will assist research into the mechanistic stratification of INS. Samples and data will be available through a Strategic Access and Oversight Committee.

Indexed as

biobankfocal segmental glomerulosclerosisidiopathic nephrotic syndromeminimal change disease

Identifiers

PMID39135942
PMCPMC11317841

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.