Evidence map›Paper›PMID 39135750›Full record

ArticleCell stress2024

Dynamics of cell membrane lesions and adaptive conductance under the electrical stress.

Mantas Silkunas, Olga N Pakhomova, Giedre Silkuniene, Andrei G Pakhomov

Abstract read
In one paragraph

Article in Cell stress, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Impact of pulse duration on cardiac electroporation: nanosecond pulses enhance cardiomyocyte selectivity and promote a Raman-detected shift towards apoptotic cell death.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mantas SilkunasFrank Reidy Research Center for Bioelectrics, Old Dominion University VA, Norfolk USA.
Olga N PakhomovaFrank Reidy Research Center for Bioelectrics, Old Dominion University VA, Norfolk USA.
Giedre SilkunieneFrank Reidy Research Center for Bioelectrics, Old Dominion University VA, Norfolk USA.
Andrei G PakhomovFrank Reidy Research Center for Bioelectrics, Old Dominion University VA, Norfolk USA.ORCID https://orcid.org/0000-0003-3816-3860

Funding

Targeted Neuromodulation by Nanosecond Pulsed Electric FieldsR21EY034258 · NEI · OLD DOMINION UNIVERSITY · PI PAKHOMOV, ANDREI G · 2022 to 2024
$640k
Next Generation Temporal Interference Stimulation for Non-Invasive NeuromodulationR21EY034803 · NEI · OLD DOMINION UNIVERSITY · PI PAKHOMOV, ANDREI G · 2023 to 2025
$640k
NEI NIH HHS R21 EY034258NEI NIH HHS R21 EY034803
6 · The paper itself

Abstract

Exceeding physiological limits of the cell membrane potential compromises structural integrity, enabling the passage of normally impermeant solutes and disrupting cell function. Electropermeabilization has been studied extensively at the cellular scale, but not at the individual membrane lesion level. We employed fast total internal reflection fluorescence (TIRF) imaging of Ca

Indexed as

electropermeabilizationelectroporationmembrane lesionsmembrane repairTIRF

Identifiers

PMID39135750
PMCPMC11318148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.