Evidence map›Paper›PMID 39135706›Full record

ArticleFrontiers in physiology2024

Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.

Thomas Kjeld, Anders Brenøe Isbrand, Henrik Christian Arendrup, Jens Højberg, Jacob Bejder, Thomas O Krag, John Vissing, Lars Poulsen Tolbod, Johannes Hendrik Harms, Lars Christian Gormsen and 2 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Advances in breath-hold diving research: a state-of-the-art review.European journal of applied physiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas KjeldDepartment of Anesthesiology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Anders Brenøe IsbrandDepartment of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.
Henrik Christian ArendrupDepartment of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.
Jens HøjbergDepartment of Cardiothoracic Anesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jacob BejderDepartment of Nutrition, Exercise and Sport (NEXS), University of Copenhagen, Copenhagen, Denmark.
Thomas O KragDepartment of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
John VissingDepartment of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Lars Poulsen TolbodDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Johannes Hendrik HarmsDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Lars Christian GormsenDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Dan FugløDepartment of Nuclear Medicine, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Egon Godthaab HansenDepartment of Anesthesiology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Elite breath-hold divers (BHD) possess several oxygen conserving adaptations to endure long dives similar to diving mammals. During dives, Bottlenose Dolphins may increase the alveolar ventilation (V Methods and results: Pulmonary blood volume (PBV) was determined by echocardiography, Conclusion: Our results contrast with previous studies, that demonstrated similar lung gas transfer in BHD and matched controls. We conclude that elite BHD 1) have a lower diffusion constant than matched controls, and 2) gradually decrease PBV during apnea and in turn increase V New and noteworthy: This manuscript addresses novel knowledge on tolerance to hypoxia during diving, which is shared by elite breath-hold divers and adult diving mammals: Our study indicates that elite breath-hold divers gradually decrease pulmonary blood volume and in turn increase VA/Q, to increase alveolar oxygen delivery during maximum apnea to tolerate decreasing oxygen levels similar to the Bottlenose Dolphin.

Indexed as

cardiac MR (CMR)cardiac outputcardiac PET/CTechocardiagraphyfreediving

Identifiers

PMID39135706
PMCPMC11318387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.