Evidence map›Paper›PMID 39135692›Full record

ArticleiMeta2024

MASS cohort: Multicenter, longitudinal, and prospective study of the role of microbiome in severe pneumonia and host susceptibility.

Xin Wei, Li Guo, Hongliu Cai, Silan Gu, Lingling Tang, Yuxin Leng, Minghui Cheng, Guojun He, Yijiao Han, Xindie Ren and 26 more

Abstract read
In one paragraph

Article in iMeta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Review
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Xin WeiLife Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.ORCID 0000-0001-6635-5531
Li GuoNHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Hongliu CaiDepartment of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Silan GuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Lingling TangDepartment of Infectious Diseases Shulan (Hangzhou) Hospital Hangzhou China.
Yuxin LengDepartment of Intensive Care Unit Peking University Third Hospital Beijing China.
Minghui ChengLife Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.
Guojun HeDepartment of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Yijiao HanDepartment of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Xindie RenDepartment of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Baoyue LinDepartment of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Longxian LvState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Huanzhang ShaoDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital; Zhengzhou University People's Hospital Henan University People's Hospital Zhengzhou China.
Mingqiang WangDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital; Zhengzhou University People's Hospital Henan University People's Hospital Zhengzhou China.
Hongyu WangDepartment of Emergency Intensive Care Unit The Fifth Clinical Medical College of Henan University of Chinese Medicine Zhengzhou China.
Dan DangDepartment of Critical Care Medicine Xi'an People's Hospital (Xi'an No.4 Hospital) Xi'an China.
Shengfeng WangDepartment of Critical Care Medicine The Second Affiliated Hospital of Zhengzhou University Zhengzhou China.
Nan WangDepartment of Critical Care Medicine The Second Affiliated Hospital of Zhengzhou University Zhengzhou China.
Peng ShenDepartment of Critical Care Medicine The First Hospital of Jiaxing Jiaxing China.
Qianqian WangDepartment of Critical Care Medicine The First Hospital of Jiaxing Jiaxing China.
Yinghe XuDepartment of Critical Care Medicine Taizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University Taizhou China.
Yongpo JiangDepartment of Critical Care Medicine Taizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University Taizhou China.
Ning ZhangDepartment of Critical Care Medicine Lishui People's Hospital Lishui China.
Xuwei HeDepartment of Critical Care Medicine Lishui People's Hospital Lishui China.
Xuntao DengDepartment of Critical Care Medicine Lishui People's Hospital Lishui China.
Muhua DaiDepartment of Critical Care Medicine Tongde Hospital of Zhejiang Province Hangzhou China.
Lin ZhongDepartment of Critical Care Medicine The First People's Hospital of Pinghu Pinghu China.
Yonghui XiongDepartment of Critical Care Medicine Lanxi Hospital of Traditional Chinese Medicine Lanxi China.
Yujie PanDepartment of Critical Care Medicine Wenzhou Central Hospital Wenzhou China.
Kankai TangDepartment of Critical Care Medicine The First People's Hospital of Huzhou Huzhou China.
Fengqi LiuDepartment of Critical Care Medicine The First People's Hospital of Huzhou Huzhou China.
Bin YangCenter for Infectious Diseases Vision Medicals Co., Ltd. Guangzhou Guangdong China.
Lili RenNHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Jianwei WangNHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Chao JiangLife Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.ORCID 0000-0003-0260-7271
Lingtong HuangLife Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MASS cohort comprises 2000 ICU patients with severe pneumonia, covering community-acquired pneumonia, hospital-acquired pneumonia, and ventilator-associated pneumonia, sourced from 19 hospitals across 10 cities in three provinces. A wide array of samples including bronchoalveolar lavage fluid, sputum, feces, and whole blood are longitudinally collected throughout patients' ICU stays. The cohort study seeks to uncover the dynamics of lung and gut microbiomes and their associations with severe pneumonia and host susceptibility, integrating deep metagenomics and transcriptomics with detailed clinical data.

Identifiers

PMID39135692
PMCPMC11316923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.