Evidence map›Paper›PMID 39135654›Full record

ArticleAccess microbiology2024

Effect of chemotherapeutic agents on natural transformation frequency in Acinetobacter baylyi.

Macaulay Winter, Michiel Vos, Angus Buckling, Pål Jarle Johnsen, Klaus Harms

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Access microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Macaulay WinterEuropean Centre for Environment and Human Health, University of Exeter Medical School, Penryn Campus, Exeter TR10 9FE, UK.ORCID 0000-0001-5491-5685
Michiel VosEuropean Centre for Environment and Human Health, University of Exeter Medical School, Penryn Campus, Exeter TR10 9FE, UK.
Angus BucklingEnvironment and Sustainability Institute, University of Exeter, Penryn Campus, Penryn TR10 9FE, UK.
Pål Jarle JohnsenMicrobial Pharmacology and Population Biology Research Group, Department of Pharmacy, Faculty of Health Sciences, UiT, The Arctic University of Norway, Tromsø, Norway.
Klaus HarmsMicrobial Pharmacology and Population Biology Research Group, Department of Pharmacy, Faculty of Health Sciences, UiT, The Arctic University of Norway, Tromsø, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural transformation is the ability of a bacterial cell to take up extracellular DNA which is subsequently available for recombination into the chromosome (or maintenance as an extrachromosomal element). Like other mechanisms of horizontal gene transfer, natural transformation is a significant driver for the dissemination of antimicrobial resistance. Recent studies have shown that many pharmaceutical compounds such as antidepressants and anti-inflammatory drugs can upregulate transformation frequency in the model species

Indexed as

Acinetobacter baylyiantimicrobial resistancecancer chemotherapeutic agentsnatural transformation

Identifiers

PMID39135654
PMCPMC11318045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.