Evidence map›Paper›PMID 39135640›Full record

ReviewFrontiers in cellular and infection microbiology2024

Gut microbiome: a novel preventive and therapeutic target for prostatic disease.

Hongliang Cao, Difei Zhang, Pengyu Wang, Yishu Wang, Chengdong Shi, Hao Wu, Hao Du, Wenqiang Zhang, Zixuan Gou, Honglan Zhou and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongliang CaoDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Difei ZhangKey Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, China.
Pengyu WangDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Yishu WangKey Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, China.
Chengdong ShiDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Hao WuDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Hao DuDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Wenqiang ZhangDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Zixuan GouBethune First Clinical School of Medicine, The First Hospital of Jilin University, Changchun, China.
Honglan ZhouDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.
Song WangDepartment of Urology II, The First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiome (GM) impacts various physiological processes and can lead to pathological conditions and even carcinogenesis if homeostasis is disrupted. Recent studies have indicated a connection between the GM and prostatic disease. However, the underlying mechanisms are still unclear. This review aims to provide a summary of the existing information regarding the connection between the GM and various prostatic conditions such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), benign prostatic hyperplasia (BPH), and prostate cancer (PCa). Furthermore, the review aims to identify possible pathogenic mechanisms and suggest potential ways of targeting GM to prevent and treat prostatic disease. Due to the complexity of the mechanism between GM and prostatic diseases, additional research is required to comprehend the association between the two. This will lead to more effective treatment options for prostatic disease.

Indexed as

Gastrointestinal MicrobiomeProstatic DiseasesDietFecal Microbiota TransplantationHumansInflammationMaleMedicine, Chinese TraditionalMetabolomebenign prostatic hyperplasiagut microbiomeprostate cancerprostatitistherapy

Identifiers

PMID39135640
PMCPMC11317475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.