Evidence map›Paper›PMID 39135176›Full record

ArticleBMC biotechnology2024

Comparison of lipidome profiles in serum from lactating dairy cows supplemented with Acremonium terrestris culture based on UPLC-QTRAP-MS/MS.

Chenmiao Zhang, Yiran Zhao, Shijiao Guo, Feifei Li, Xu Gong, Jiarui Gao, Linshu Jiang, Jinjin Tong

Erratum issuedAbstract readComparative Study
In one paragraph

Article in BMC biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Evaluation of Lipid Changes During the Drying Process ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Chenmiao Zhang *Animal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Yiran Zhao *Animal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Shijiao Guo *Animal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Feifei LiAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Xu GongAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Jiarui GaoAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Linshu JiangAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China.
Jinjin TongAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, P. R. China. tongjinjin0451@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of supplementing the diet of lactating cows with Acremonium terrestris culture (ATC) on milk production, serum antioxidant capacity, inflammatory indices, and serum lipid metabolomics. Over 90 days, 24 multiparous Chinese Holstein cows in mid-lactation (108 ± 10.4 days in milk, 637 ± 25 kg body weight, 30.23 ± 3.7 kg/d milk yield) were divided into either a control diet (CON) or a diet supplemented with 30 g of ATC daily. All the data were analyzed using Student's t test with SPSS 20.0 software. The results showed that compared with CON feeding, ATC feeding significantly increased milk yield, antioxidant capacity, and immune function. Lipidome screening identified 143 lipid metabolites that differed between the two groups. Further analysis using "random forest" machine learning revealed three glycerophospholipid serum metabolites that could serve as lipid markers with a predictive accuracy of 91.67%. This study suggests that ATC can be a useful dietary supplement for improving lactational performance in dairy cows and provides valuable insights into developing nutritional strategies to maintain metabolic homeostasis in ruminants.

Indexed as

AcremoniumDietary SupplementsLactationLipidomicsTandem Mass SpectrometryAnimal FeedAnimalsAntioxidantsCattleChromatography, High Pressure LiquidFemaleLipidsMilkAntioxidantsLipidsAcremonium terrestris cultureBiotransformationGlycerophospholipidsLipidomicsSphingolipids

Identifiers

PMID39135176
PMCPMC11318124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.