Evidence map›Paper›PMID 39135060›Full record

ArticleBMC medicine2024

Recent cervical cancer incidence, stage at diagnosis, and mortality trends in Puerto Rico, 2001-2019.

Ana P Ortiz, Carlos R Torres-Cintrón, Eduardo J Santiago-Rodríguez, Jeslie M Ramos-Cartagena, Tonatiuh Suárez-Ramos, Haluk Damgacioglu, Vivian Colón-López, Karen J Ortiz-Ortiz, Ashish A Deshmukh

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06943547 (The Effectiveness, Cost-effectiveness, and Budget Impact of Interventions to Improve the Delivery of Cervical Cancer Screening in Puerto Rico), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06943547 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

The Effectiveness, Cost-effectiveness, and Budget Impact of Interventions to Improve the Delivery of Cervical Cancer Screening in Puerto Rico

TypeinterventionalSponsorUniversity of Puerto Rico Comprehensive Cancer CenterRan2025 to 2028Enrolled1,400ConditionsCervical Cancer ScreeningArmsArm 2: Patient Navigator, HPV self-collection kit
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cancer statistics for Hispanic/Latino people, 2026.CA: a cancer journal for clinicians
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana P OrtizUniversity of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico. ana.ortiz7@upr.edu.
Carlos R Torres-CintrónComprehensive Cancer Center, Puerto Rico Central Cancer Registry, Cancer Control and Population Sciences Division, University of Puerto Rico, San Juan, Puerto Rico.
Eduardo J Santiago-RodríguezUniversity of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico.
Jeslie M Ramos-CartagenaUniversity of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico.
Tonatiuh Suárez-RamosComprehensive Cancer Center, Puerto Rico Central Cancer Registry, Cancer Control and Population Sciences Division, University of Puerto Rico, San Juan, Puerto Rico.
Haluk DamgaciogluDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
Vivian Colón-LópezUniversity of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico.
Karen J Ortiz-OrtizUniversity of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico.
Ashish A DeshmukhDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.

Funding

UPR/MDACC Partnership for Excellence in Cancer Research(Parent Grant U54 CA096297)U54CA096297 · NCI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI KAREN J ORTIZ · 2002 to 2026
$36.9M
UPR/MDACC Partnership for Excellence in Cancer Research (Luis Segarra supplement)U54CA096300 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHARON Hermes GIORDANO, Paul A Scheet · 2002 to 2026
$23.8M
The effectiveness, cost-effectiveness, and budget impact of interventions to improve the delivery of cervical cancer screening in Puerto Rico.R01CA282424 · NCI · COMPREHENSIVE CANCER CENTER/ UNIV/PR · PI Ashish A. Deshmukh, ANA Patricia ORTIZ · 2023 to 2026
$2.4M
NCI NIH HHS R01 CA282424NCI NIH HHS U54 CA096297NCI NIH HHS U54 CA096300
6 · The paper itself

Abstract

backgroundCervical cancer incidence is rising in Puerto Rico (PR). Whether the increase is real or reflective of increased diagnostic scrutiny remains unclear.

methodsUsing data from the PR Central Cancer Registry for 2001-2019, we estimated trends of hysterectomy-corrected cervical cancer incidence and mortality rates, overall, and by stage at diagnosis and age.

resultsOverall, cervical cancer incidence (per 100,000) increased 1.6%/year (95% CI, -0.5% to 3.8%) from 12.5 to 15.3, with a prominent increase in distant-stage disease (4.5%/year [95% CI, 1.6% to 8.0%]), particularly among screening age eligible (25-64-year-old) women (5.8%/year [95% CI, 2.1% to 10.6%]). Mortality rates in this age-group remained stable during the study period.

conclusionsIncreased occurrence of distant-stage disease among screening-eligible women is troubling and may reflect a real increase. Future research is needed to elucidate the factors underlying these trends. Improved prevention is also an urgent priority to reverse the rising cervical cancer incidence in PR.

Indexed as

Uterine Cervical NeoplasmsAdolescentAdultAgedFemaleHumansIncidenceMiddle AgedNeoplasm StagingPuerto RicoRegistriesYoung AdultCervical cancerEpidemiologyIncidenceMortalityPuerto Rico

Identifiers

PMID39135060
PMCPMC11320972

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.