Evidence map›Paper›PMID 39134890›Full record

ArticleSpine deformity2024

Improving prediction of progression of idiopathic scoliosis based on curve size and skeletal maturity.

Kevin M Neal, Melanie Boeyer, Emily C Craver, Julia E Crook, Gary M Kiebzak

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In one paragraph

Article in Spine deformity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kevin M NealNemours Children's Health, 807 Children's Way, Jacksonville, FL, 32207, USA. kevin.neal@nemours.org.ORCID 0000-0002-8870-8286
Melanie BoeyerUniversity of Missouri School of Medicine, Columbia, MO, USA.ORCID 0000-0001-7518-472X
Emily C CraverMayo Clinic College of Medicine, Jacksonville, FL, USA.ORCID 0000-0003-0334-9606
Julia E CrookMayo Clinic College of Medicine, Jacksonville, FL, USA.ORCID 0000-0001-9932-925X
Gary M KiebzakNemours Children's Health, 807 Children's Way, Jacksonville, FL, 32207, USA.ORCID 0000-0002-4638-9571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo define the risk of curve progression of idiopathic scoliosis (IS) to 35°, 40°, 45°, and 50° based on current curve magnitude and Sanders stage for boys and girls, using a large cohort of patients and encounters, to improve granularity and allow more accurate estimations to guide treatment.

methodsRetrospective analysis of a prospectively collected scoliosis database. Generalized estimation equation logistic regression models estimated probabilities of curve progression to 35°, 40°, 45°, and 50° based on starting curve size and Sanders stage. Probabilities and their 95% confidence intervals were calculated for each combination of variables to each endpoint separately for boys and girls.

resultsA total of 309 patients (80% girls) were included. Starting curve size and Sanders stage were significant predictors for progression in both sexes (all P ≤ 0.04). Higher starting curve sizes and lower Sanders stages were associated with greater odds of progression. Risk of progression was still present even at higher Sanders stages.

conclusionIS curves follow a predictable pattern, having more risk for progression when curves are larger and Sanders stages are smaller. Risk of curve progression is a spectrum based on these factors, indicating some risk of progression exists even for many smaller curves with higher Sanders stages. The improved granularity of this analysis compared to prior efforts may be useful for counseling patients about the risks of curve progression to various curve size endpoints and may aid shared decision-making regarding treatments. LEVEL OF EVIDENCE OR CLINICAL RELEVANCE: Level III: retrospective cohort study.

Indexed as

Disease ProgressionScoliosisAdolescentChildFemaleHumansMaleRetrospective StudiesSpineCurve progressionIdiopathic scoliosisNatural historyPrediction modelSanders stage

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.