Trial reportJournal of perinatology : official journal of the California Perinatal Association2024
Impact of breast milk on cortical pain response in newborns during the heel prick procedure: a randomized controlled trial.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05961904 (Impact of Breast Milk on Cortical Pain Response in Newborns During the Heel Prick Procedure), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Breast Milk on Cortical Pain Response in Newborns During the Heel Prick Procedure: A Randomized Controlled Trial
Who cites it
4 citing papers in PubMed.
- Efficacy of Expressed Breast Milk Versus Sweet Solutions for Neonatal Procedural Pain: A Systematic Review and Meta-Analysis.Biomedicines · 2026Review
- Effectiveness of Sucrose Versus Breast Milk as Non-Pharmacological Measures in the Management of Neonatal Pain: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- An Effect of Smelled Breast Milk During and After Venous Blood Drawing on Newborn Infants' Pain and Comfort Level.Healthcare (Basel, Switzerland) · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effects of breast milk on cortical pain response and behavioral response in newborns during heel-prick procedure. STUDY
designA prospective, randomized controlled trial was conducted on healty-term newborns, undergoing heel blood sampling. Infants were randomly assigned to study group with receive orally 2 ml breast milk (n = 45) or a control group with no intervention (n = 45). A near-infrared spectroscopy device was used to monitor regional cerebral oxygen saturation (rScO
resultsThe N-PASS score (p = 0.001) and the crying time (p = 0.017) were significantly lower in the study group compared to the control group. Although the mean rScO
conclusionBreast milk administration decreases behavioral responses to a noxious stimulus without reducing the cortical response to pain. CLINICAL
trial registrationThis trial was registered under ClinicalTrials.gov identifier no. NCT05961904.
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Identifiers
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Registered trials
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