ArticleScientific reports2024
Comprehensive analysis of risk factors for flap necrosis in free flap reconstruction of postoperative tissue defects in oral and maxillofacial tumors.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Incidence and risk factors for postoperative vascular crisis in patients with oral and maxillofacial cancer: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Risk Factors for Surgical Site Infection in Patients with Oral Cancer: A Systematic Review.Annals of surgical oncology · 2025Pooled it
- Incidence of flap-related complications in the oral reconstruction area after free flap reconstruction in patients with oral cancer.World journal of surgical oncology · 2025Pooled it
- Cutibacterium avidum Bacteria in Post-Mastectomy Breast with Prior Silicone Injections, Singapore.Emerging infectious diseases · 2026Article
- Complication drivers in head and neck free flap surgery: A single-center predictive analysis.Oral and maxillofacial surgery · 2026Article
- Autonomization of Microvascular Free Flaps in Reconstructive Surgery: A Narrative Review.Microsurgery · 2026Review
- A nomogram for predicting free flap necrosis in soft tissue reconstruction of lower limbs: a retrospective cohort study.Frontiers in medicine · 2026Article
- Risk factors associated with postoperative necrosis after digital replantation: a systematic review and meta-analysis.Frontiers in surgery · 2026Review
- Functional nutritional frailty predicts complications after microvascular free flap reconstruction.Frontiers in surgery · 2026Article
- [Interventional revascularization combined with perforator composite flap for staged treatment of peripheral arterial disease with ankle soft tissue defects].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Article
- From injury to reconstruction, utilizing staged technique in a self-inflicted facial gunshot wound: a case report.Journal of medical case reports · 2025Article
- Non-Tobacco Nicotine Use and Complications in Free Flap Repair in Head and Neck Cancer.The Laryngoscope · 2025Article
- Microvascular free flaps in head and neck reconstruction: an analysis of outcomes in elderly patients.Clinical oral investigations · 2025Article
- Donor site outcomes and functional recovery are improved with superficial inferior epigastric artery perforator flap compared to radial forearm flap in oral and maxillofacial reconstruction.American journal of translational research · 2025Article
- Development and validation of a Nomogram to predict postoperative flap necrosis risk in breast cancer patients undergoing modified radical mastectomy.American journal of cancer research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Free flap reconstruction for postoperative tissue defects in oral and maxillofacial tumors is a critical component of reconstructive surgery. Identifying risk factors for flap necrosis is essential for improving surgical outcomes and patient quality of life. A retrospective study was conducted on patients who underwent free flap reconstruction between January 2020 and December 2023. Patients were included if they had comprehensive medical records and at least a six-month follow-up. We excluded those with a history of flap necrosis, uncontrolled systemic diseases, non-adherence to postoperative care, or concurrent malignancy treatments. Data on demographics, comorbidities, flap characteristics, and operative details were collected and analyzed using univariate analysis and logistic regression tests. Univariate analysis did not find a significant correlation between flap necrosis and factors such as hyperlipidemia, lymph node metastasis, or flap type. However, diabetes mellitus, oral infections, and albumin levels below 35 g/L were significantly associated with flap necrosis. Multivariate logistic regression showed diabetes mellitus increased the odds of flap necrosis by approximately ninefold, and oral infection increased it by over tenfold. Diabetes mellitus, oral infection, and low albumin levels are significant risk factors for flap necrosis in free flap reconstruction after oral and maxillofacial surgery. Prompt identification and management of these factors are crucial to mitigate the risk of flap necrosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.