Evidence map›Paper›PMID 39134376›Full record

ArticleAJNR. American journal of neuroradiology2025

Safety and Technical Performance of Bilateral Decubitus CT Myelography Using Standard versus Increased Intrathecal Iodinated Contrast Volume.

Diogo G L Edelmuth, Renata V Leão, Eduardo N K Filho, Marcio N P Souza, Marcelo Calderaro, Peter G Kranz

Abstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diogo G L EdelmuthFrom the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (D.G.L.E., R.V.L., M.N.P.S., M.C.), São Paulo, SP, Brazil diogo.e@hc.fm.usp.br.ORCID 0000-0003-0567-0823
Renata V LeãoFrom the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (D.G.L.E., R.V.L., M.N.P.S., M.C.), São Paulo, SP, Brazil.
Eduardo N K FilhoDepartment of Radiology (D.G.L.E., R.V.L., E.N.K.F.), Hospital Sírio-Libanês, São Paulo, SP, Brazil.
Marcio N P SouzaFrom the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (D.G.L.E., R.V.L., M.N.P.S., M.C.), São Paulo, SP, Brazil.
Marcelo CalderaroFrom the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (D.G.L.E., R.V.L., M.N.P.S., M.C.), São Paulo, SP, Brazil.
Peter G KranzDepartment of Radiology (P.G.K.), Duke University Hospital, Durham, North Carolina.ORCID 0000-0001-5410-7135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeLateral decubitus CT myelography (LDCTM) is one of the main studies for the detection of CSF-venous fistulas, but detection of CSF-venous fistulas is dependent on intrathecal contrast attenuation. The purpose of this investigation was to assess the tolerability and technical performance of increased intrathecal doses of myelographic contrast compared with standard doses. MATERIALS AND

methodsThis is a retrospective series of 24 patients who underwent LDCTM following administration of either 10 or 20 mL of intrathecal iodinated contrast media (300 or 320 mg/mL of iodine content). Patients were scanned in the initial lateral decubitus position and then turned to the contralateral side and re-scanned in the same session. The safety and tolerability of the 20 mL dose was assessed from clinical records. The technical performance of the studies was compared between groups (10 or 20 mL) by measuring attenuation values over the lateral thecal sac at standardized levels. Both the initial scan and the scan after turning the patient to the contralateral side were assessed.

resultsNo moderate or severe adverse event was recorded in either group. The 20-mL group showed higher attenuation values, which were statistically greater on the second side examined compared with the standard-dose group.

conclusionsIncreased volume of intrathecal contrast was well-tolerated and improved the technical performance of LDCTM in this limited series. Further assessment of the safety and impact on diagnostic yield using larger patient cohorts is warranted.

Indexed as

Contrast MediaMyelographyTomography, X-Ray ComputedAdultAgedAged, 80 and overDose-Response Relationship, DrugFemaleHumansInjections, SpinalMaleMiddle AgedReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityContrast Media

Identifiers

PMID39134376
PMCPMC11878965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.