ArticleAJNR. American journal of neuroradiology2025
"Flow Void Sign": Flow Artifact on T2-Weighted MRI Can Be an Indicator of Dural Defect Location in Ventral Type 1 Spinal CSF Leaks.
Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Temporal and regional trends in the diagnosis and treatment of spontaneous intracranial hypotension: a systematic review.The journal of headache and pain · 2026Pooled it
- Interpreting acute postoperative MRI after lumbar spinal fusion: a practical framework for clinical decision-making.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Diagnostic Value of Flow-Void Sign for Localizing Ventral Dural Defects in Spine MRI.Journal of clinical neurology (Seoul, Korea) · 2026Article
- A dural displacement sign in patients with type 1 cerebrospinal fluid leakage.Neuroradiology · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with spontaneous intracranial hypotension caused by type 1 dural defects typically have an epidural fluid collection on MRI. Still, the location of the defect is not usually readily identifiable on standard MRI sequences and can be at any point along the length of the collection. The most common location for type 1 leaks is ventral and, as such, these are most commonly associated with ventral predominant epidural fluid. Dynamic myelography (either digital subtraction myelography or dynamic CT myelography) is currently the standard of care for localizing the defect. We describe an imaging sign on T2-weighted images caused by CSF-flow egress at the site of the defect that may permit accurate prediction of the site of the CSF leak noninvasively. Importantly, this sign was only observed on 2D T2-weighted and STIR images and not on 3D acquisitions, which notably suppress artifacts. This has implications for optimal MRI spine protocol construction. This sign can be used to limit myelographic range, reduce radiation dose, and increase diagnostic confidence in dural defect location.
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