Evidence map›Paper›PMID 39133769›Full record

ArticleJournal of veterinary internal medicine

Use of sedation-awakening electroencephalography in dogs with epilepsy.

Marcin Wrzosek, Aleksandra Banasik, Adriana Czerwik, Agnieszka Olszewska, Marta Płonek, Veronika Stein

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcin WrzosekDepartment of Internal Diseases with a Clinic for Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.ORCID https://orcid.org/0000-0002-8963-6253
Aleksandra BanasikDepartment of Internal Diseases with a Clinic for Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.ORCID https://orcid.org/0000-0001-5775-1022
Adriana CzerwikDepartment of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University, Giessen, Germany.ORCID https://orcid.org/0000-0001-6545-5370
Agnieszka OlszewskaDepartment of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University, Giessen, Germany.
Marta PłonekEvidensia Small Animal Hospital, Arnhem, The Netherlands.
Veronika SteinDivision of Clinical Neurology, Department for Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-4482-869X

Funding

Wrocław University of Environmental and Life Sciences
6 · The paper itself

Abstract

backgroundElectroencephalography (EEG) recording protocols have been standardized for humans. Although the utilization of techniques in veterinary medicine is increasing, a standard protocol has not yet been established. HYPOTHESIS: Assessment of a sedation-awakening EEG protocol in dogs. ANIMALS: Electroencephalography examination was performed in a research colony of 6 nonepileptic dogs (control [C]) and 12 dogs with epilepsy admitted to the clinic because of the epileptic seizures.

methodsIt was a prospective study with retrospective control. Dogs with epilepsy were divided into 2 equal groups, wherein EEG acquisition was performed using a "sedation" protocol (IE-S, n = 6) and a "sedation-awakening" protocol (IE-SA, n = 6). All animals were sedated using medetomidine. In IE-SA group, sedation was reversed 5 minutes after commencing the EEG recording by injecting atipamezole IM. Type of background activity (BGA) and presence of EEG-defined epileptiform discharges (EDs) were evaluated blindly. Statistical significance was set at P > 0.05.

resultsEpileptiform discharges were found in 1 of 6 of the dogs in group C, 4 of 6 of the dogs in IE-S group, and 5 of 6 of the dogs in IE-SA group. A significantly greater number of EDs (spikes, P = .0109; polyspikes, P = .0109; sharp waves, P = .01) were detected in Phase 2 in animals subjected to the "sedation-awakening" protocol, whereas there was no statistically significant greater number of discharges in sedated animals. CONCLUSIONS AND CLINICAL IMPORTANCE: A "sedation-awakening" EEG protocol could be of value for ambulatory use if repeated EEG recordings and monitoring of epilepsy in dogs is needed.

Indexed as

Dog DiseasesElectroencephalographyEpilepsyHypnotics and SedativesMedetomidineAnimalsDogsFemaleImidazolesMaleProcedural SedationProspective StudiesRetrospective StudiesatipamezoleHypnotics and SedativesImidazolesMedetomidineambulatory EEGcanine electroencephalographycanine epilepsy diagnosisepilepsyparoxysmalsedationseizure

Identifiers

PMID39133769
PMCPMC11423447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.