Evidence map›Paper›PMID 39133260›Full record

ArticleCardiovascular drugs and therapy2025

Exercise Enhances Anti-contractile Effects of PVAT Through Endogenous H

Chaoge Wang, Linjie Shu, Ran Cheng, Mengsi Yan, Wenhao Liang, Jie Zhou, Niujin Shi, Lidan Chen, Linyu Peng, Junhao Huang and 2 more

Abstract read
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In one paragraph

Article in Cardiovascular drugs and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chaoge Wang *Guangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Linjie Shu *Guangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Ran ChengGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Mengsi YanGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Wenhao LiangGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Jie ZhouGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Niujin ShiGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Lidan ChenGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Linyu PengGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Junhao HuangGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China.
Min HuGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China. minhu@gzsport.edu.cn.
Jingwen LiaoGuangdong Provincial Key Laboratory of Sports and Health Promotion, Guangzhou Sport University, Tianhe District, 1268 Guangzhou Avenue Middle, Guangzhou, 510500, No, China. liaojw@gzsport.edu.cn.ORCID 0000-0002-4438-5577

Funding

Guangzhou Basic Research Plan, Basic and Applied Basic Research Project SL2023A04J00446National Natural Science Foundation of China 31801005National Natural Science Foundation of China 31971105
6 · The paper itself

Abstract

purposeHydrogen sulfide (H

methodsAfter the establishment of obesity hypertension (24 weeks) through a high-fat diet, male Sprague-Dawley rats were randomly assigned to control group (HC), exercise group (HE), cystathionine γ-lyase (CSE) blocking group (HCB), and exercise combined with CSE blocking group (HEB). Exercise and CSE inhibitor regimens were performed throughout 13 weeks.

resultsAfter 13 weeks of intervention, blood pressure was significantly decreased by long-term exercise (HC vs. HE, P < 0.05) but not by exercise combined with the CSE inhibitor regimen. Meanwhile, the CSE inhibitor significantly blocked the production of H

conclusionsThese results collectively suggest that endogenous H

Indexed as

Adipose TissueDiet, High-FatHydrogen SulfideHypertensionObesityPhysical Conditioning, AnimalVasoconstrictionAnimalsBlood PressureCystathionine gamma-LyaseDisease Models, AnimalMaleRatsRats, Sprague-DawleyCystathionine gamma-LyaseHydrogen SulfideHydrogen sulfideLong-term exerciseObesityPerivascular adipose tissue

Identifiers

PMID39133260

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.