Evidence map›Paper›PMID 39133231›Full record

ArticleBioresources and bioprocessing2024

Production of rare ginsenosides by biotransformation of Panax notoginseng saponins using Aspergillus fumigatus.

Lian Yang, Dongmei Lin, Feixing Li, Xiuming Cui, Dengji Lou, Xiaoyan Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lian YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China.
Dongmei LinFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China.
Feixing LiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China.
Xiuming CuiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China.
Dengji LouSchool of Chemical, Biological and Environmental Sciences, Yuxi Normal University, Yuxi, 653100, People's Republic of China. loudengji@yxnu.edu.cn.
Xiaoyan YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China. yangxiaoyan9999@163.com.

Funding

National Natural Science Foundation of China 32060104
6 · The paper itself

Abstract

Panax notoginseng saponins (PNS) are the main active components of Panax notoginseng. But after oral administration, they need to be converted into rare ginsenosides by human gut microbiota and gastric juice before they can be readily absorbed into the bloodstream and exert their effects. The sources of rare ginsenosides are extremely limited in P. notoginseng and other medical plants, which hinders their application in functional foods and drugs. Therefore, the production of rare ginsenosides by the transformation of PNS using Aspergillus fumigatus was studied in this research. During 50 days at 25 ℃ and 150 rpm, A. fumigatus transformed PNS to 14 products (1-14). They were isolated by varied chromatographic methods, such as silica gel column chromatography, Rp-C

Indexed as

Antimicrobial activityAspergillus fumigatusBiotransformationPanax notoginseng saponinsRare ginsenosides

Identifiers

PMID39133231
PMCPMC11319572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.