Evidence map›Paper›PMID 39133022›Full record

ArticleAntimicrobial agents and chemotherapy2024

Efficacy of aspergillomarasmine A/meropenem combinations with and without avibactam against bacterial strains producing multiple β-lactamases.

Caitlyn M Rotondo, Gerard D Wright

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Lanthipeptides fromMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Revisiting the Metallo-International journal of microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Caitlyn M RotondoDavid Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-1654-7903
Gerard D WrightDavid Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-9129-7131

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) PJT183745
6 · The paper itself

Abstract

The effectiveness of β-lactam antibiotics is increasingly threatened by resistant bacteria that harbor hydrolytic β-lactamase enzymes. Depending on the class of β-lactamase present, β-lactam hydrolysis can occur through one of two general molecular mechanisms. Metallo-β-lactamases (MBLs) require active site Zn

Indexed as

Anti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesEscherichia coliMeropenemMicrobial Sensitivity TestsAspartic Acidbeta-Lactamase InhibitorsDrug CombinationsDrug Resistance, Multiple, BacterialEnterobacter cloacaeHumansKlebsiella pneumoniaePseudomonas aeruginosaAnti-Bacterial AgentsAspartic Acidaspergillomarasmine AavibactamAzabicyclo Compoundsbeta-Lactamase Inhibitorsbeta-LactamasesDrug CombinationsMeropenemantibiotic resistanceaspergillomarasmine Abeta-lactamscarbapenemscephemsmetallo-beta-lactamasespenamsserine-beta-lactamases

Identifiers

PMID39133022
PMCPMC11373191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.