Evidence map›Paper›PMID 39132612›Full record

ArticleGastro hep advances2023

Timely Albumin Improves Survival in Patients With Cirrhosis on Diuretic Therapy Who Develop Acute Kidney Injury: Real-World Evidence in the United States.

Ray W Kim, Karthik Raghunathan, Greg S Martin, E Anne Davis, Navreet S Sindhwani, Santosh Telang, Kunal Lodaya

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Article in Gastro hep advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ray W KimDivision of Gastroenterology and Hepatology, Stanford University, Stanford, California.
Karthik RaghunathanDepartment of Anesthesiology, Duke University, Durham, North Carolina.
Greg S MartinDepartment of Medicine, Emory University, Atlanta, Georgia.
E Anne DavisGrifols Shared Services North America (SSNA), Research Triangle Park, North Carolina.
Navreet S SindhwaniGrifols Shared Services North America (SSNA), Research Triangle Park, North Carolina.
Santosh TelangBoston Strategic Partners, Inc, Boston, Massachusetts.
Kunal LodayaBoston Strategic Partners, Inc, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Patients admitted with decompensated cirrhosis who develop acute kidney injury (AKI) tend to experience poor outcomes, even if provided with increased organ support such as renal replacement therapies. We assessed the association of albumin administered ≤24 hours of admission with hospital length of stay (LOS) and in-hospital mortality. Methods: The Cerner Health Facts Database was queried for hospitalized patients with cirrhosis who had >0.3 mg/dL increase in serum creatinine within 48 hours and received diuretics following admission between January 2009 and April 2018. This study received institutional review board exemption through federal regulation 45CFR46. Albumin infusion was "timely" if administered ≤24 hours after admission and "nontimely" if administered >24 hours after admission or not at all. Two subgroups were assessed: the AKI Results: A total of 4135 hospitalizations with cirrhosis and AKI were grouped into AKI Conclusion: Among patients with cirrhosis and AKI, treatment with albumin ≤24 hours after admission was associated with a shorter LOS and lower risk of death in patients with stage 3 AKI.

Indexed as

AKIDecompensationIn-Hospital MortalityLength of Stay

Identifiers

PMID39132612
PMCPMC11307587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.