Evidence map›Paper›PMID 39132531›Full record

ArticleJournal of the Society for Cardiovascular Angiography & Interventions

Propensity-Matched Outcomes Comparing TAVR in Bicuspid vs Surgery in Tricuspid Aortic Valve Stenosis.

G Michael Deeb, Steven J Yakubov, Michael J Reardon, Basel Ramlawi, Stan J Chetcuti, Neal S Kleiman, Firas Zahr, Howard K Song, Hemal Gada, Mubashir Mumtaz and 3 more

Abstract read
In one paragraph

Article in Journal of the Society for Cardiovascular Angiography & Interventions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

G Michael DeebDepartments of Cardiac Surgery and Interventional Cardiology, University of Michigan Hospitals, Ann Arbor, Michigan.
Steven J YakubovDepartment of Interventional Cardiology, Riverside Methodist-OhioHealth, Columbus, Ohio.
Michael J ReardonDepartments of Interventional Cardiology and Cardiothoracic Surgery, and, Houston Methodist DeBakey Heart and Vascular Institute, Houston, Texas.
Basel RamlawiDepartment of Cardiothoracic Surgery, Valley Health, Winchester, Virginia.
Stan J ChetcutiDepartments of Cardiac Surgery and Interventional Cardiology, University of Michigan Hospitals, Ann Arbor, Michigan.
Neal S KleimanDepartments of Interventional Cardiology and Cardiothoracic Surgery, and, Houston Methodist DeBakey Heart and Vascular Institute, Houston, Texas.
Firas ZahrDepartments of Cardiothoracic Surgery and Interventional Cardiology, Oregon Health and Science University, Portland, Oregon.
Howard K SongDepartments of Cardiothoracic Surgery and Interventional Cardiology, Oregon Health and Science University, Portland, Oregon.
Hemal GadaDepartments of Interventional Cardiology and Cardiothoracic Surgery, University of Pittsburgh Pinnacle, Wormsleyburg, Pennsylvania.
Mubashir MumtazDepartments of Interventional Cardiology and Cardiothoracic Surgery, University of Pittsburgh Pinnacle, Wormsleyburg, Pennsylvania.
Saki ItoDivision of Cardiovascular Ultrasound, Mayo Clinic, Rochester, Minnesota.
Jian HuangDepartment of Statistics, Medtronic, Minneapolis, Minnesota.
John K ForrestDepartment of Internal Medicine (Cardiology), Yale University School of Medicine, New Haven, Connecticut.

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002369
6 · The paper itself

Abstract

Objective: To compare 1-year outcomes in patients at low surgical risk with bicuspid aortic valve stenosis (AS) following transcatheter aortic valve replacement (TAVR) and low-risk patients with tricuspid AS following surgical aortic valve replacement (SAVR). Background: The pivotal randomized, prospective, multicenter TAVR trials compared TAVR vs SAVR in patients with tricuspid AS. No such trials exist for bicuspid AS. Methods: The Low Risk Bicuspid Study is a prospective, single-arm, TAVR trial that enrolled 150 patients from 25 sites in the United States. A screening committee confirmed bicuspid anatomy and valve classification based on computed tomography using the Sievers classification. Annular measurements guided valve sizing. These patients were propensity-matched to the SAVR patients in the randomized Evolut Low Risk Trial using 1:1 5-to-1-digit Greedy method, resulting in 144 matched pairs. For both trials, an independent clinical events committee adjudicated all serious adverse events, and the same independent core laboratory assessed all echocardiograms. Results: The 1-year composite of death, disabling stroke, or aortic valve-related rehospitalization for bicuspid TAVR vs tricuspid SAVR was 6 (4.2%) vs 6 (4.2%) ( Conclusions: In this select group of low-risk bicuspid patients, in the short-term follow-up, TAVR appears to have similar outcomes to those seen in comparable low-risk tricuspid patients undergoing SAVR.

Indexed as

aortic stenosisbicuspid aortic valvesupra-annulartranscatheter aortic valve replacement

Identifiers

PMID39132531
PMCPMC11307701

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.