Evidence map›Paper›PMID 39132472›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Relating Standardized Automated Perimetry Performed with Stimulus Sizes III and V in Eyes With Field Loss due to Glaucoma and NAION.

David Szanto, Michael Wall, Luke X Chong, Mark J Kupersmith

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David SzantoDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York.ORCID 0000-0002-4640-4655
Michael WallDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa.ORCID 0000-0002-9802-4806
Luke X ChongSchool of Medicine, Deakin University, Geelong, Australia.ORCID 0000-0001-5694-4500
Mark J KupersmithDepartments of Neurology, Ophthalmology and Neurosurgery, CNIIC, Icahn School of Medicine at Mount Sinai, NY.ORCID 0000-0002-5675-2434

Funding

Statistical Unsupervised Learning VF for IIHTT & ONTTR21EY032522 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KUPERSMITH, MARK J · 2021 to 2022
$495k
NEI NIH HHS R21 EY032522
6 · The paper itself

Abstract

Objective: Standard automated perimetry (SAP) visual field (VF) results are more repeatable using Goldmann stimulus size V (stimV) in eyes with moderate/severe deficits due to glaucoma. There are few reports relating VFs using stimulus size V and III, typically used in the clinic for glaucoma, and none for non-arteritic anterior ischemic optic neuropathy (NAION). We hypothesized that we could compare and relate the VFs with both stimuli for glaucoma and NAION. Methods: We utilized 1992 same-day pairs of stimIII and stimV SAP VFs using the 24-2 strategy for eyes with glaucoma or NAION. We explored the optimal threshold to censor the raw sensitivities, prior to calculating age-standardized total deviations (TD). We determined the mean and standard deviation of the differences among all TD pairs. We computed a line of best fit to determine closeness to the line of unity. Results: The ideal censoring conversion threshold was 21 dB for stimIII and 24 dB for stimV. The difference between stimV and stimIII censored (0.0 ± 1.9 dB) and uncensored (0.4 ± 2.6 dB) TD pairings strongly correlate with each other (r Conclusion: Censoring plus age correction is a valid method of comparison between stimIII and stimV SAP VFs with moderate to severe VF loss due to optic nerve disorders. Translational Relevance: StimIII and stimV TDs are interchangeable in clinical practice.

Identifiers

PMID39132472
PMCPMC11312634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.