Evidence map›Paper›PMID 39132462›Full record

ArticleJournal of the Society for Cardiovascular Angiography & Interventions2024

Ultrasound-Assisted Versus Standard Catheter-Directed Thrombolysis for Acute Pulmonary Embolism: Insights From National Inpatient Sample.

Islam Shatla, Mahmoud El Iskandarani, Muhammad Zia Khan, Ahmed Elkaryoni, Ayman Elbadawi, Sachin S Goel, Marwan Saad, Sudarshan Balla, Amir Darki, Islam Y Elgendy

Abstract read
In one paragraph

Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Islam ShatlaDepartment of Internal Medicine, Kansas University Medical Center, Kansas City, Kansas.
Mahmoud El IskandaraniDepartment of Internal Medicine, Eastern Connecticut Health Network, Manchester, Connecticut.
Muhammad Zia KhanDivision of Cardiovascular Disease, West Virginia University Heart and Vascular Institute, Morgantown, West Virginia.
Ahmed ElkaryoniLifespan Cardiovascular Institute and Division of Cardiovascular Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Ayman ElbadawiDivision of Cardiovascular Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Sachin S GoelDivision of Cardiovascular Medicine, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas.
Marwan SaadLifespan Cardiovascular Institute and Division of Cardiovascular Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Sudarshan BallaDivision of Cardiovascular Disease, West Virginia University Heart and Vascular Institute, Morgantown, West Virginia.
Amir DarkiDivision of Cardiovascular Medicine, Loyola University Medical Center, Maywood, Illinois.
Islam Y ElgendyDivision of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, Kentucky.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary embolism is one of the leading causes of morbidity and mortality in the United States. Catheter-directed therapies have emerged as a promising treatment for managing intermediate- and high-risk patients; however, data comparing standard catheter-directed thrombolysis (SCDT) and ultrasound-assisted thrombolysis (USAT) are limited. This study aimed to investigate trends, outcomes, and predictors of mortality of both modalities from a nationally representative sample. Methods: This analysis used data from the National Inpatient Sample years 2016-2020. The primary outcome was in-hospital mortality. A multivariable regression model was used to compare the outcomes. Results: Among 39,430 patients who received catheter-directed thrombolysis, 26,710 (76.8%) received SCDT and 8060 (23.2%) received USAT. The utilization of SCDT and USAT increased during the study years except for 2020. In-hospital mortality was lower among patients who received USAT (2.7% vs 3.8%; Conclusions: Ultrasound-assisted thrombolysis was associated with similar in-hospital mortality and bleeding complications compared with SCDT for acute pulmonary embolism. Further studies are warranted to confirm evaluate the long-term outcomes with both modalities.

Indexed as

catheter-directed thrombolysispulmonary embolismultrasound-assisted thrombolysis

Identifiers

PMID39132462
PMCPMC11308128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.