ArticleEuropean heart journal. Case reports2024
Misconception of 'malignant' and 'scissor-like compression' of interarterial course in anomalous aortic origin of a coronary artery: a case series.
Article in European heart journal. Case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Quantitative and qualitative CT features of coronary artery anomalies with an interarterial course: exploratory associations with exertional symptoms.The international journal of cardiovascular imaging · 2026Article
- Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography.Frontiers in cardiovascular medicine · 2026Article
- Anomalous right coronary artery stemming from left coronary sinus and malignant interarterial course in a middle-aged woman: a case report and review of diagnostic and surgical management.International journal of emergency medicine · 2025Article
- Multi-Modality Imaging in Coronary Anomalies: Focus on Anomalous Aortic Origin of Coronary Arteries.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Catheterization Techniques for Anomalous Aortic Origin of Coronary Arteries.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Review
- Hemodynamic Relevance Evaluation of Coronary Artery Anomaly During Stress Using FFR/IVUS in an Artificial Twin.JACC. Case reports · 2025Article
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Authors and funding
5 authors.
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Abstract
Background: The notion that the 'interarterial' segment of anomalous aortic origin of a coronary artery (AAOCA) is 'malignant' and 'scissor-like' compressed between the aorta and pulmonary artery (PA) is debated, owing to the lower pressure in the pulmonary system compared with that in the coronary system. However, data supporting or refuting this belief under stress conditions are lacking. Case summary: Three cases of right AAOCA with interarterial/intramural courses (52, 66, and 51 years old) were assessed. Invasively measured fractional flow reserve (FFR) under dobutamine was 0.85, 0.82, and 0.81, respectively. Intravascular ultrasound illustrated lateral vessel compression of the intramural course with a decrease of minimal lumen area (MLA) (i.e. 5.71-3.47 mm Conclusion: This case series challenges the assumption that the interarterial segment of AAOCA is scissor-like compressed by both the aorta and PA. The decrease in MLA and FFR under stress is due to the aorta's unidirectional lateral compression on the intramural segment. Additionally, the term 'malignant' should not be universally applied to all AAOCA cases with an interarterial course, as not all result in haemodynamic significance.
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