ArticleJournal of the Society for Cardiovascular Angiography & Interventions
SCAI Guidelines for the Management of Patent Foramen Ovale.
Article in Journal of the Society for Cardiovascular Angiography & Interventions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 112 papers.
What it found
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The trial behind it
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Who cites it
112 citing papers in PubMed.
- Trial
- Patent Foramen Ovale: Epidemiology, Risk Factors, Pathophysiology, Clinical Features, Diagnosis, and Management.MedComm · 2026Review
- Percutaneous Closure of Patent Foramen Ovale in a Patient With Incomplete Cor Triatriatum Sinister: A Case Report.Journal of clinical ultrasound : JCU · 2026Article
- Zero-fluoroscopy, intracardiac echocardiography-only patent foramen ovale closure in early pregnancy: a case report.European heart journal. Case reports · 2026Article
- Article
- Observational
- Diagnostic Yield of Comprehensive Etiologic Evaluation in Young Adults with Ischemic Stroke: Toward a Phenotype-Driven Approach.Journal of clinical medicine · 2026Article
- Heart-Rate-Dependent Right-to-Left Shunting Through a Patent Foramen Ovale in Severe Right Ventricular Dysfunction: A Case Report.Journal of clinical medicine · 2026Article
- Oxygen-Refractory Platypnea-Orthodeoxia Syndrome Requiring Urgent Surgical Closure: A Dynamic Assessment.JACC. Case reports · 2026Article
- DCI With Severe Portal Venous Gas Embolism After Cave Diving in a Diver With a PFO.JACC. Case reports · 2026Article
- Persistent Hypoxia After Tricuspid Valve Replacement.JACC. Case reports · 2026Article
- Beyond Tunnel Length: Tunnel Width-Derived Cover Index Improves Device Sizing and Predicts Outcomes After Transcatheter Patent Foramen Ovale Closure.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Persistent (patent) foramen ovale assessment and closure for the general physician.Clinical medicine (London, England) · 2026Review
- When Pulmonary Embolism Opens the Door: Paradoxical Thalamic Stroke Through a Patent Foramen Ovale.Cureus · 2026Article
- Concurrent Patent Foramen Ovale and Pulmonary Arteriovenous Malformation Etiology: Complex Case of Cryptogenic Stroke.JACC. Case reports · 2026Article
- Transcatheter Patent Foramen Ovale Closure and Complete Remission of Migraine in Children: A Single-Center Retrospective Cohort Study.Pediatric cardiology · 2026Article
- Methodology and baseline characteristics of the China Migraine registry (CHIME): a nationwide, multi-center, prospective cohort study of 11,814 patients.The journal of headache and pain · 2026Observational
- Platypnea-orthodeoxia syndrome in an 86-year-old woman with a patent foramen ovale.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Atrial Thrombus in Severe Pectus Excavatum and Patent Foramen Ovale Closure.JACC. Case reports · 2026Article
- Diagnosis and Management of Patent Foramen Ovale for Stroke Prevention: An Australian and New Zealand Consensus Statement Developed by a Modified Nominal Group Approach.The Medical journal of Australia · 2026Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patent foramen ovale (PFO) is a vestigial congenital cardiovascular structure present in around 25% of adults. In most cases, PFO is entirely benign and requires no treatment. However, it may cause serious complications under certain circumstances. Objective: These evidence-based guidelines from the Society for Cardiovascular Angiography and Interventions (SCAI) aim to support patients, clinicians, and other stakeholders in decisions about management of PFO. Methods: SCAI convened a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest. The Evidence Foundation, a registered 501(c)(3) nonprofit organization, provided methodological support for the guideline-development process. Following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, the guideline panel formulated and prioritized clinical questions in population, intervention, comparison, outcome (PICO) format. A separate technical review team of clinical and methodological experts conducted systematic reviews of the evidence, synthesized data, and graded the certainty of the evidence across outcomes. The guideline panel then reconvened to formulate recommendations and supporting remarks informed by the results of the technical review and additional contextual factors described in the GRADE evidence-to-decision framework. Results: The panel agreed on 13 recommendations to address variations on 5 clinical scenarios. Conclusions: Key recommendations address patient selection for PFO closure in the prevention of recurrent PFO-associated stroke, including populations not commonly included in randomized studies, and scenarios where the PFO closure might serve a role in the prevention of other outcomes such as migraine headaches and decompression illness. The panel has also identified future research priorities to advance the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.