Evidence map›Paper›PMID 39131568›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2024

Improving radiological quantification of levator hiatus features with measures informed by statistical shape modeling.

Vincenzia S Vargo, Megan R Routzong, Pamela A Moalli, Ghazaleh Rostaminia, Steven D Abramowitch

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vincenzia S VargoUniversity of Pittsburgh, Department of Bioengineering, Pittsburgh, Pennsylvania, United States.ORCID https://orcid.org/0009-0005-5802-2151
Megan R RoutzongUniversity of Pittsburgh, Department of Bioengineering, Pittsburgh, Pennsylvania, United States.ORCID https://orcid.org/0000-0001-5551-1156
Pamela A MoalliUniversity of Pittsburgh, Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Surgery, Pittsburgh, Pennsylvania, United States.
Ghazaleh RostaminiaNorthShore University Health System, University of Chicago Pritzker School of Medicine, Division of Urogynecology, Female Pelvic Medicine and Reconstructive Surgery, Skokie, Illinois, United States.
Steven D AbramowitchUniversity of Pittsburgh, Department of Bioengineering, Pittsburgh, Pennsylvania, United States.ORCID https://orcid.org/0000-0001-7762-7723

Funding

Porosity and tensioning: Critical factors to consider when choosing a prolapse meshR01HD083383 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ABRAMOWITCH, STEVEN D, MOALLI, PAMELA A. · 2016 to 2025
$5.5M
TRAINING IN REPRODUCTIVE SCIENCEST32HD007203 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAMELA L MELLON · 1988 to 2026
$4.8M
Overcoming complications of polypropylene prolapse meshes: Development of novel elastomeric membranesR01HD097187 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI Katrina Marquita Knight, Pamela A. Moalli · 2019 to 2026
$3.9M
NICHD NIH HHS R01 HD083383NICHD NIH HHS R01 HD097187NICHD NIH HHS T32 HD007203
6 · The paper itself

Abstract

Purpose: The measures that traditionally describe the levator hiatus (LH) are straightforward and reliable; however, they were not specifically designed to capture significant differences. Statistical shape modeling (SSM) was used to quantify LH shape variation across reproductive-age women and identify novel variables associated with LH size and shape. Approach: A retrospective study of pelvic MRIs from 19 nulliparous, 32 parous, and 12 pregnant women was performed. The LH was segmented in the plane of minimal LH dimensions. SSM was implemented. LH size was defined by the cross-sectional area, maximal transverse diameter, and anterior-posterior (A-P) diameter. Novel SSM-guided variables were defined by regions of greatest variation. Multivariate analysis of variance (MANOVA) evaluated group differences, and correlations determined relationships between size and shape variables. Results: Overall shape ( Conclusions: The traditional maximal transverse diameter generally corresponded with SSM findings but cannot describe anterior and posterior variation independently. The novel anterior and posterior transverse diameters represent both size and shape variation, can be easily calculated alongside traditional measures, and are more sensitive to subtle and local LH variation. Thus, they have a greater ability to serve as predictive and diagnostic parameters.

Indexed as

levator ani muscleslevator hiatus dimensionsparitypelvic MRIstatistical shape modeling

Identifiers

PMID39131568
PMCPMC11316399

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.