Evidence map›Paper›PMID 39131562›Full record

ArticleGastro hep advances2023

Defining and Phenotyping Gastric Abnormalities in Long-Term Type 1 Diabetes Using a Novel Body Surface Gastric Mapping Device.

William Xu, Armen A Gharibans, Stefan Calder, Gabriel Schamberg, Anthony Walters, Jia Jang, Chris Varghese, Daniel Carson, Charlotte Daker, Stephen Waite and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Gastro hep advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06411574 (Comparing the Impact of Body Surface Gastric Mapping and Gastric Emptying Scintigraphy on Clinical Management in Suspected Gastroparesis), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06411574 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparing the Impact of Body Surface Gastric Mapping and Gastric Emptying Scintigraphy on Clinical Management in Suspected Gastroparesis

TypeinterventionalSponsorUniversity of Western SydneyRan2024 to 2026Enrolled40ConditionsGastroparesisArmsGastric Alimetry
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Gastric AlimetryJournal of clinical medicine · 2023
    Review
  13. Review
  14. Comparison of Gastric AlimetryScientific reports · 2023
    Article
  15. Gastric sensorimotor function and its clinical measurement.Neurogastroenterology and motility · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

William XuDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Armen A GharibansDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Stefan CalderDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Gabriel SchambergDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Anthony WaltersLiggins Institute, University of Auckland, Auckland, New Zealand.
Jia JangDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Chris VargheseDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Daniel CarsonDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Charlotte DakerAlimetry Ltd, Auckland, New Zealand.
Stephen WaiteAlimetry Ltd, Auckland, New Zealand.
Christopher N AndrewsAlimetry Ltd, Auckland, New Zealand.
Tim CundyDepartment of Medicine, University of Auckland, Auckland, New Zealand.
Gregory O'GradyDepartment of Surgery, The University of Auckland, Auckland, New Zealand.

Funding

Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping TechniqueR56DK126935 · NIDDK · UNIVERSITY OF LOUISVILLE · PI ABELL, THOMAS LYMAN, O'GRADY, GREG · 2021 to 2021
$450k
NIDDK NIH HHS R56 DK126935
6 · The paper itself

Abstract

Background and Aims: Diabetic gastroenteropathy is associated with poor glycemic control and morbidity in people with type 1 diabetes (T1D). There is a lack of noninvasive techniques to assess and monitor gastric abnormalities. We aimed to define phenotypes of gastric myoelectrical abnormalities in people with longstanding T1D with and without symptoms using a novel noninvasive body surface gastric mapping (BSGM) device. Methods: BSGM was performed on people with T1D of >10 years duration and matched controls, employing Gastric Alimetry (Alimetry, New Zealand), comprising of a high-resolution 64-channel array, validated symptom-logging App, and wearable reader. Results: Thirty-two people with T1D were recruited (15 with a high symptom burden), and 32 controls. Those with symptoms showed more unstable gastric myoelectrical activity (Gastric Alimetry Rhythm Index 0.39 vs 0.51, Conclusion: Gastric symptoms in people with longstanding T1D correlate with myoelectrical abnormalities on BSGM evaluation, in addition to glycemic control, psychological comorbidities, and peripheral neuropathy. BSGM using Gastric Alimetry identified a range of myoelectrical phenotypes, presenting targets for diagnosis, monitoring, and therapy.

Indexed as

Diabetes MellitusDyspepsiaElectrogastrographyFunctional Gastrointestinal DisordersGastroparesis

Identifiers

PMID39131562
PMCPMC11307485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.