Evidence map›Paper›PMID 39131365›Full record

ArticlebioRxiv : the preprint server for biology2024

Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus.

Sam McKenzie, Alexandra L Sommer, Tia N Donaldson, Infania Pimentel, Meenakshi Kakani, Irene Jungyeon Choi, Ehren L Newman, Daniel F English

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sam McKenzieDepartment of Neurosciences, University of New Mexico Health Science Center, Albuquerque, NM 87106.ORCID 0000-0002-0492-0950
Alexandra L SommerDepartment of Neurosciences, University of New Mexico Health Science Center, Albuquerque, NM 87106.
Tia N DonaldsonDepartment of Neurosciences, University of New Mexico Health Science Center, Albuquerque, NM 87106.
Infania PimentelDepartment of Neurosciences, University of New Mexico Health Science Center, Albuquerque, NM 87106.
Meenakshi KakaniDepartment of Neurosciences, University of New Mexico Health Science Center, Albuquerque, NM 87106.
Irene Jungyeon ChoiPsychological and Brain Sciences, Indiana University, Bloomington, IN, 47405.
Ehren L NewmanPsychological and Brain Sciences, Indiana University, Bloomington, IN, 47405.ORCID 0000-0001-7006-4112
Daniel F EnglishSchool of Neuroscience, Virginia Tech, Blacksburg, VA, 24061.ORCID 0000-0003-2284-870X

Funding

Investigation into the synaptic origins of hippocampal replayR00MH118423 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MCKENZIE, SAMUEL ARNOLD · 2020 to 2022
$923k
NIMH NIH HHS R00 MH118423
6 · The paper itself

Abstract

Episodic memories are temporally segmented around event boundaries that tend to coincide with moments of environmental change. During these times, the state of the brain should change rapidly, or reset, to ensure that the information encountered before and after an event boundary is encoded in different neuronal populations. Norepinephrine (NE) is thought to facilitate this network reorganization. However, it is unknown whether event boundaries drive NE release in the hippocampus and, if so, how NE release relates to changes in hippocampal firing patterns. The advent of the new GRAB

Identifiers

PMID39131365
PMCPMC11312532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.