Evidence map›Paper›PMID 39131314›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis.

Sajad Hamid Ahanger, Chujing Zhang, Evan R Semenza, Eugene Gil, Mitchel A Cole, Li Wang, Arnold R Kriegstein, Daniel A Lim

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sajad Hamid AhangerDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-9531-6221
Chujing ZhangDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0009-0008-6790-6006
Evan R SemenzaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-3494-6542
Eugene GilDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-2658-7976
Mitchel A ColeDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-0708-3542
Li WangDepartment of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-9510-6294
Arnold R KriegsteinDepartment of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-5742-2990
Daniel A LimDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-7221-3425

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
Functional long noncoding RNAs in neural developmentR01NS124881 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL A LIM · 2022 to 2026
$3.0M
Understanding the neurodevelopmental role and mechanism of histone demethylase JMJD3R01NS112357 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIM, DANIEL A · 2020 to 2024
$1.9M
BD FACSAria Fusion Cell SorterS10OD021822 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, MICHAEL R. · 2016 to 2016
$573k
Identifying mechanisms ofsynapse maturation at neuronal subtype resolutionK99MH131832 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, LI · 2023 to 2024
$182k
Role of MLL Chromatin Remodeling Factor in Neural Stem CellsI01BX000252 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI DANIEL A LIM · 2009 to 2026
–
BLRD VA I01 BX000252NIDDK NIH HHS P30 DK063720NIH HHS S10 OD021822NIMH NIH HHS K99 MH131832NINDS NIH HHS R01 NS112357NINDS NIH HHS R01 NS124881
6 · The paper itself

Abstract

The nuclear genome is spatially organized into a three-dimensional (3D) architecture by physical association of large chromosomal domains with subnuclear compartments including the nuclear lamina at the radial periphery and nuclear speckles within the nucleoplasm

Identifiers

PMID39131314
PMCPMC11312588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.