Evidence map›Paper›PMID 39131208›Full record

ArticleBrazilian journal of veterinary medicine2024

Analysis of VEGFR-2 and PDGFR-β expression in canine splenic hemangiosarcoma to identify drug repositioning candidates.

Igor Simões Tiagua Vicente, Fernanda Barthelson Carvalho de Moura, Juliana Moreira Rozolen, Denner Santos Dos Anjos, Renata Afonso Sobral, Carlos Eduardo Fonseca Alves

Abstract read
In one paragraph

Article in Brazilian journal of veterinary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Igor Simões Tiagua VicenteVeterinarian, DSc., VetPrecision Laboratory, Botucatu, SP, Brazil.ORCID 0000-0003-4213-3947
Fernanda Barthelson Carvalho de MouraVeterinarian, Departamento de Cirurgia Veterinária e Reprodução Animal, Escola de Medicina Veterinária e Zootecnia, Universidade Estadual de São Paulo (UNESP), Botucatu, SP, Brazil.ORCID 0000-0002-8153-2038
Juliana Moreira RozolenVeterinarian, MSc., Departamento de Cirurgia Veterinária e Reprodução Animal, Escola de Medicina Veterinária e Zootecnia, UNESP, Botucatu, SP, Brazil.ORCID 0000-0001-5441-1057
Denner Santos Dos AnjosVeterinarian, DSc., Departamento de Cirurgia Veterinária e Reprodução Animal, Escola de Medicina Veterinária e Zootecnia, UNESP, Botucatu, SP, Brazil.ORCID 0000-0003-1804-475X
Renata Afonso SobralVeterinarian, DSc., Onco Cane Veterinary, São Paulo, SP, Brazil.ORCID 0000-0001-8868-6243
Carlos Eduardo Fonseca AlvesVeterinarian, DSc., VetPrecision Laboratory, Botucatu, SP, Brazil.ORCID 0000-0002-6702-6139

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic tumors are very common in dogs, and canine hemangiosarcoma (HSA) is one of the most important malignant splenic tumors. Surgery followed by chemotherapy (anthracycline-based protocols) is recommended for treating canine HSA; however, patients still do not achieve long-term survival. Therefore, this research aimed to assess vascular endothelial growth factor receptor-2 (

Indexed as

dogsdrug repurposingendothelial cellsspleen

Identifiers

PMID39131208
PMCPMC11315467

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.